Results 231 to 240 of about 822,699 (313)

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

Advances in BODIPY Derivatives for Antibacterial Phototherapy

Angewandte Chemie, EarlyView.
This review systematically summarizes the design strategies and structure‐activity relationships of BODIPY‐based antibacterial phototherapy, covering molecular engineering of small‐molecule photosensitizers and nanoplatforms, bacterial targeting and carrier design, and discussing the challenges and future perspectives associated with clinical ...
Li Lv, Heejeong Kim, Hongchen Zhai, Hanqi Ren, Silu Wang, Cong Sun, Yafu Wang, Hosoowi Lee, Juyoung Yoon, Hua Zhang   +9 more
wiley   +2 more sources

Measuring and Targeting Persistent Inflammation in Chronic Coronary Disease. [PDF]

JACC Adv
Frangogiannis NG.
europepmc   +1 more source

Tunable Regional Targeting of Self‐Assembling Peptide Nanomaterials in Acute Myocardial Infarction

Advanced NanoBiomed Research, EarlyView.
In a rat model of acute myocardial infarction, intravascular delivery of peptide nanofibers with a collagen‐targeting peptide bound to the infarct vasculature while globular peptide nanoparticles penetrated into the infarct area. This study demonstrated that size, shape, and surface chemistry of nanomaterials control the delivery location within the ...
Alexander Chen, Michael B. Nguyen, Elliot Widd, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Houston Harding, Chloe Hurteau, Anika Yogi, Colin Luo, Rebecca L. Braden, Pedro Cabrales, Karen L. Christman   +14 more
wiley   +1 more source

The Rome project of coronary heart disease prevention

, 1984
Research Group of the Rome Project of Coronary Heart Disease Prevention, ARCA, Marcello   +1 more
core  

An Ounce of Prevention for a Pound of Cure?: Lipid-Lowering Therapy for Premature Coronary Disease. [PDF]

JACC Adv
Khurshid S, Kany S.
europepmc   +1 more source

Cost-effectiveness of low-dose colchicine in patients with chronic coronary disease in The Netherlands. [PDF]

Eur Heart J Qual Care Clin Outcomes
Fiolet ATL, Keusters W, Blokzijl J, Nidorf SM, Eikelboom JW, Budgeon CA, Tijssen JGP, Römer T, Westendorp I, Cornel JH, Thompson PL, Frederix GWJ, Mosterd A, de Wit GA.   +13 more
europepmc   +1 more source

Revertant Mosaicism Obscures Long‐Awaited Molecular Confirmation of Diamond‐Blackfan Anemia

American Journal of Medical Genetics Part A, EarlyView.
Nicholas A. Borja, Mustafa Tekin
wiley   +1 more source

Correction to: Myocardial infarction with non-obstructive coronary arteries as compared with myocardial infarction and obstructive coronary disease: outcomes in a Medicare population. [PDF]

Eur Heart J
europepmc   +1 more source

Minimally invasive coronary bypass grafting for treating multivessel coronary disease: A single-center prospective pilot study. [PDF]

JTCVS Open
Ding T, Gong Y, Fu Y, Cui Z, Wu S, Yang W, Yang H, Zhao H, Feng H, Zheng H, Meng L, Guo R, Han H, Ling Y.   +13 more
europepmc   +1 more source