Results 221 to 230 of about 1,254,536 (301)

Minimally Invasive vs Conventional Coronary Bypass Surgery for Multivessel Coronary Disease. [PDF]

Ann Thorac Surg Short Rep
Gong Y, Ding T, Wang X, Cui Z, Zhao H, Wu S, Fu Y, Yang H, Ling Y.   +8 more
europepmc   +1 more source

Metabolic and biochemical profiling reveals phenotypic heterogeneity in Zucker diabetic fatty rats

Animal Models and Experimental Medicine, EarlyView.
Genetically uniform Zucker Diabetic Fatty (ZDF) rats spontaneously develop four distinct metabolic phenotypes despite identical housing and diet conditions. Each phenotype exhibits unique biomarker signatures encompassing glucose homeostasis, insulin secretion, polyol pathway activation, oxidative stress, inflammatory cytokines, and neurotrophic ...
Marek Lepáček, Pavol Boďo, Barbora Kaločayová, Marta Šoltésová Prnová   +3 more
wiley   +1 more source

Predictive Value of Residual SYNTAX Score II for Patients With Complex Coronary Disease and Chronic Renal Insufficiency After Percutaneous Coronary Intervention. [PDF]

Rev Cardiovasc Med
Zhang S, Lei Y, Chen J, Wang Y, Liu H, Guo N, Wang Y, Cao X, Yan L.   +8 more
europepmc   +1 more source

Complementary multi‐omics profiling of chronic thromboembolic pulmonary hypertension reveals immune cell alterations, epigenetic changes, and genetically supported candidate genes

Animal Models and Experimental Medicine, EarlyView.
This study presents an integrative multi‐omics framework to uncover the molecular mechanisms and potential biomarkers of chronic thromboembolic pulmonary hypertension (CTEPH). Anthropometric and biochemical data were correlated using canonical correlation analysis, revealing key cardiometabolic associations. Single‐cell RNA sequencing identified immune
Xiaopeng Liu, Xia Zheng, Yajun Zhang, Yinghui Fang, Yanan Zhen   +4 more
wiley   +1 more source

Strategies for chronic coronary disease: A brief guide for clinicians. [PDF]

NPJ Cardiovasc Health
Krittanawong C, Khawaja M, Virk HUH, Escobar J, Khalid U, Birnbaum Y, Lavie CJ, Sharma S, Jneid H, Rao S, Virani SS.   +10 more
europepmc   +1 more source

A high‐fat diet with vitamin D and propylthiouracil produces a pro‐atherogenic phenotype in rats

Animal Models and Experimental Medicine, EarlyView.
Male Sprague–Dawley rats received a cholesterol‐rich high‐fat diet supplemented with vitamin D and propylthiouracil for 11 weeks. The model induced dyslipidemia (increased total cholesterol/low‐density lipoprotein, decreased triglycerides), inflammation (increased interleukin‐6 and serum amyloid A), hypercalcemia, and reduced circulating endothelial ...
Angélique Lewies, Vitaris Kodogo, Johannes Frederik Wentzel, Francis Edwin Smit   +3 more
wiley   +1 more source

VEGF-A cis-located SNPs on human chromosome 6 associated with VEGF-A plasma levels and survival in a coronary disease cohort. [PDF]

BMC Cardiovasc Disord
Meza-Alvarado JC, Pilbrow AP, Frampton CM, Cameron VA, Richards AM, Troughton RW, Doughty RN, Page RA, Mallard B, Bromhead C, Palmer BR.   +10 more
europepmc   +1 more source

Age and gender effects on echocardiographic and histopathological cardiac phenotypes in healthy adult mice

Animal Models and Experimental Medicine, EarlyView.
This study investigated the impact of age and sex on cardiac phenotypes in healthy adult C57BL/6J mice using echocardiography and histopathological analyses. Findings revealed that female mice demonstrated more pronounced global cardiac chamber dilation during aging.
Shuang Wen, Xijia Shao, Xiulin Zhang, Ningning Zhang, Xiao Chen, Guangxin Yue, Jiangping Song   +6 more
wiley   +1 more source

Changes in coronary disease management decisions in real-world practice between 2015 and 2023: insights from the EVAREST/BSE-NSTEP observational study. [PDF]

Eur Heart J Cardiovasc Imaging
Johnson CL, Krasner S, Woodward W, Mao E, McCourt A, Dockerill C, Balkhausen K, Chandrasekaran B, Kardos A, Sabharwal N, Firoozan S, Sarwar R, Senior R, Sharma R, Wong K, Augustine DX, Paton M, O'Driscoll J, Oxborough D, Pearce K, Robinson S, Willis J, Leeson P, EVAREST/BSE-NSTEP Investigators.   +23 more
europepmc   +1 more source

The HCMV‐encoded miR‐UL36‐3p promotes angiogenesis of endothelial cells by downregulating FOXO3

Animal Models and Experimental Medicine, EarlyView.
This illustration shows the role of hcmv‐miR‐UL36‐3p in endothelial cell angiogenesis. During productive infection, endothelial cells express HCMV‐encoded miRNAs. Viral hcmv‐miR‐UL36‐3p promotes endothelial cell proliferation, migration, and capillary tube formation by directly targeting and downregulating FOXO3. The pro‐angiogenic activity of hcmv‐miR‐
Chen Wang, Mengyu Li, Guosheng Li, Hao Zhang, Cheng Wang, Chen‐Yu Zhang   +5 more
wiley   +1 more source