Results 41 to 50 of about 170,319 (394)

A randomized, placebo-controlled trial of late Na current inhibition (ranolazine) in coronary microvascular dysfunction (CMD): impact on angina and myocardial perfusion reserve. [PDF]

, 2015
AimsThe mechanistic basis of the symptoms and signs of myocardial ischaemia in patients without obstructive coronary artery disease (CAD) and evidence of coronary microvascular dysfunction (CMD) is unclear.
Anderson, R David, Bairey Merz, C Noel, Berman, Daniel S, Brown, Garrett H, Cook-Wiens, Galen, Handberg, Eileen M, Mehta, Puja K, Minissian, Margo B, Pepine, Carl J, Petersen, John W, Rogatko, André, Shaw, Leslee J, Shufelt, Chrisandra L, Shuster, Jonathan J, Thomson, Louise EJ, Wei, Janet   +15 more
core   +1 more source

Coronary Flow Capacity to Identify Stenosis Associated With Coronary Flow Improvement After Revascularization: A Combined Analysis From DEFINE FLOW and IDEAL

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Coronary flow capacity (CFC), which is a categorical assessment based on the combination of hyperemic coronary flow and coronary flow reserve (CFR), has been introduced as a comprehensive assessment of the coronary circulation to overcome the ...
Tadashi Murai, Valérie E. Stegehuis, Tim P. van de Hoef, Gilbert W. M. Wijntjens, Masahiro Hoshino, Yoshihisa Kanaji, Tomoyo Sugiyama, Rikuta Hamaya, Sukhjinder S. Nijjer, Guus A. de Waard, Mauro Echavarria‐Pinto, Paul Knaapen, Martijn Meuwissen, Justin E. Davies, Niels van Royen, Javier Escaned, Maria Siebes, Richard L. Kirkeeide, K. Lance Gould, Nils P. Johnson, Jan J. Piek, Tsunekazu Kakuta   +21 more
doaj   +1 more source

Fractional flow reserve versus angiography in guiding management to optimize outcomes in non–ST-elevation myocardial infarction (FAMOUS-NSTEMI): rationale and design of a randomized controlled clinical trial [PDF]

, 2013
<p>Background: In patients with acute non–ST-elevation myocardial infarction (NSTEMI), coronary arteriography is usually recommended; but visual interpretation of the angiogram is subjective.
Balachandran, Kanarath P., Berry, Colin, Briggs, Andrew H., Curzen, Nick P., Das, Raj, Ford, Ian, Henderson, Robert A., Junejo, Shahid, Layland, Jamie, Oldroyd, Keith G., Sood, Arvind   +10 more
core   +1 more source

Clinical significance of PET-CT coronary flow reserve in diagnosis of non-obstructive coronary artery disease

BMC Research Notes, 2018
Objective To improve current knowledge of coronary flow reserve and non-obstructive coronary artery disease in terms of definition, features and clinical implications of measurement of coronary flow reserve (CFR), is an integrated measure of focal ...
Henry Anselmo Mayala, Khamis Hassan Bakari, Fabian Pius Mghanga, Wang ZhaoHui   +3 more
doaj   +1 more source

FFR post-PCI: what we learned from the FFR-SEARCH study

REC: Interventional Cardiology (English Ed.), 2021
WHAT DO WE KNOW ABOUT FRACTIONAL FLOW RESERVE AFTER STENTING? The introduction of the concept of fractional flow reserve (FFR) in the mid 90s moved coronary physiology from experimental science to routine use at the cath lab.1-3 Added to the better ...
Nico H.J. Pijls, Lokien X. van Nunen
doaj   +1 more source

The haemodynamic effects of collateral donation to a chronic total occlusion : implications for patient management [PDF]

, 2015
Physiological lesion assessment in the form of Fractional Flow Reserve (FFR) is now well established for the purpose of guiding multi-vessel revascularization.
Hoye, Angela, Ladwiniec, Andrew
core   +1 more source

Modern scintigraphic methods for assessing myocardial blood flow and reserve

Бюллетень сибирской медицины, 2021
Background. Today, myocardial perfusion scintigraphy is an informative and accessible method for evaluating ischemic changes in the heart. However, this method has limitations, which are more connected with a semiquantitative assessment of the study ...
A. V. Mochula, A. N. Maltseva, K. V. Zavadovsky   +2 more
doaj   +1 more source

Meta-analysis of death and myocardial infarction in the DEFINE-FLAIR and iFR-SWEDEHEART trials: a hypothesis generating note of caution [PDF]

, 2017
In patients with coronary heart disease, revascularization can improve symptoms and in certain high-risk subgroups may improve prognosis. Coronary angiography provides anatomical information and the physiological significance of a stenosis can be ...
Berry, Colin, McClure, John D., Oldroyd, Keith G.   +2 more
core   +1 more source

Coronary flow reserve by CT perfusion [PDF]

Journal of Nuclear Cardiology, 2010
Cardiovascular computed tomography (CT) is one of the most impressive advances in the non-invasive diagnosis of cardiovascular disease in the last decade. Going beyond coronary calcium scoring, cardiovascular CT is capable of identifying calcified and non-calcified plaque, percent stenosis, cardiac structure and morphology, and left ventricular ...
Frank M. Bengel, Richard T. George, Albert C. Lardo   +2 more
openaire   +2 more sources

Bimodal Pattern of Coronary Microvascular Involvement in Diabetes Mellitus

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundThe contribution of functionally disturbed coronary autoregulation and structurally impaired microvascular vasodilatory function to reduced coronary flow velocity reserve, reflecting impaired coronary microcirculation in diabetes mellitus (DM),
Murat Sezer, Mehmet Kocaaga, Emre Aslanger, Adem Atici, Ahmet Demirkiran, Zehra Bugra, Sabahattin Umman, Berrin Umman   +7 more
doaj   +1 more source