Results 61 to 70 of about 170,319 (394)

Safety of the Deferral of Coronary Revascularization on the Basis of Instantaneous Wave-Free Ratio and Fractional Flow Reserve Measurements in Stable Coronary Artery Disease and Acute Coronary Syndromes. [PDF]

open access: yes, 2018
OBJECTIVES: The aim of this study was to investigate the clinical outcomes of patients deferred from coronary revascularization on the basis of instantaneous wave-free ratio (iFR) or fractional flow reserve (FFR) measurements in stable angina pectoris ...
Al-Lamee, R   +11 more
core   +4 more sources

Accuracy of Fractional Flow Reserve Derived From Coronary Angiography

open access: yesCirculation, 2019
Background: Measuring fractional flow reserve (FFR) with a pressure wire remains underutilized because of the invasiveness of guide wire placement or the need for a hyperemic stimulus.
W. Fearon   +17 more
semanticscholar   +1 more source

Diagnostic Accuracy of a Machine-Learning Approach to Coronary Computed Tomographic Angiography–Based Fractional Flow Reserve: Result From the MACHINE Consortium

open access: yesCirculation Cardiovascular Imaging, 2018
Background: Coronary computed tomographic angiography (CTA) is a reliable modality to detect coronary artery disease. However, CTA generally overestimates stenosis severity compared with invasive angiography, and angiographic stenosis does not ...
Adriaan Coenen   +16 more
semanticscholar   +1 more source

Significance of Microvascular Function in Visual—Functional Mismatch Between Invasive Coronary Angiography and Fractional Flow Reserve

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundDespite a moderate correlation between angiographical stenosis and physiological significance, the mechanism of discordance has not been fully elucidated, particularly regarding the significance of microvascular function.
Taishi Yonetsu   +13 more
doaj   +1 more source

Pathophysiologic Basis and Diagnostic Approaches for Ischemia With Non-obstructive Coronary Arteries: A Literature Review

open access: yesFrontiers in Cardiovascular Medicine, 2022
Ischemia with non-obstructive coronary arteries (INOCA) has gained increasing attention due to its high prevalence, atypical clinical presentations, difficult diagnostic procedures, and poor prognosis.
Bingqi Fu   +7 more
doaj   +1 more source

Impairment of Coronary Flow Reserve Evaluated by Phase Contrast Cine‐Magnetic Resonance Imaging in Patients With Heart Failure With Preserved Ejection Fraction

open access: yesJournal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2016
Phase contrast (PC) cine‐magnetic resonance imaging (MRI) of the coronary sinus allows for noninvasive evaluation of coronary flow reserve (CFR), which is an index of left ventricular microvascular function. The objective of this study was to investigate
S. Kato   +12 more
semanticscholar   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Real-world clinical utility and impact on clinical decision-making of coronary computed tomography angiography-derived fractional flow reserve: lessons from the ADVANCE Registry

open access: yesEuropean Heart Journal, 2018
Aims Non-invasive assessment of stable chest pain patients is a critical determinant of resource utilization and clinical outcomes. Increasingly coronary computed tomography angiography (CCTA) with selective CCTA-derived fractional flow reserve (FFRCT ...
T. Fairbairn   +22 more
semanticscholar   +1 more source

Fractional flow reserve versus angiography for guidance of PCI in patients with multivessel coronary artery disease (FAME): 5-year follow-up of a randomised controlled trial [PDF]

open access: yes, 2015
In the Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (FAME) study, fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) improved outcome compared with angiography-guided PCI for up to 2 years of follow-up.
Barbato, Emanuele   +14 more
core   +1 more source

Coronary Flow Velocity Reserve and Survival

open access: yesJACC: Cardiovascular Imaging, 2012
Almost 40 years ago, K. Lance Gould proposed the concept of coronary flow reserve (CFR) to quantify the effect of epicardial narrowings on myocardial blood flow ([1][1]). CFR represents the extent to which hyperemic coronary flow can increase above resting flow.
Bernard De Bruyne, Martin Penicka
openaire   +3 more sources

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