Results 61 to 70 of about 33,487 (265)

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Multiphysics‐Driven Assembly of Biomimetic Vesicles

Advanced Materials, EarlyView.
Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko, Ian Gimino, Aastha Chandiwala, Bayan Alkotoub, Ali Bashiri Dezfouli, Heiko Reith, Asjad Bakhtiar, Rojda Hicsanmaz, Johann Brenner, Christoph J. O. Kaiser, Elena Belli, Shilpi Pandey, Samuel D. Rabkin, Kornelius Nielsch, Gabriele Multhoff, Oliver Hayden, Morteza Hasanzadeh Kafshgari   +16 more
wiley   +1 more source

Piezoelectric Stimulation of Neural Cells: Exploring the Synergistic Potential of Hybrid Scaffolds for Enhanced Regeneration

Advanced Materials Interfaces, EarlyView.
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton, Chris R. Bowen, Hamideh Khanbareh   +2 more
wiley   +1 more source

Functional assessment in acute coronary syndrome: a systematic review of acute versus staged interventions

REC: Interventional Cardiology (English Ed.)
Introduction and objectives: Several tools have been implemented to assess the functional significance of coronary lesions. Their reliability in the management of acute coronary syndrome (ACS) might be affected by alterations in the acute phase that go ...
Federico Vergni, Silvia Buscarini, Leonardo Ciurlanti, Filippo Luca Gurgoglione, Francesco Pellone, Mario Luzi   +5 more
doaj   +1 more source

Dynamic Single-Photon Emission Computed Tomography Data Analysis: Capabilities for Determining Functional Significance of Coronary Artery Atherosclerosis

MATEC Web of Conferences, 2016
The aim of the study was to develop the method for collecting and processing scintigraphic data to determine myocardial flow reserve by using gamma-camera with a new type detector based on Cadmium Zinc Telluride (CZT).
Mochula Andrew, Zavadovsky Konstantin, Andreev Sergey, Lishmanov Yury   +3 more
doaj   +1 more source

Smart REASSURED Sensors via Machine‐Augmented Printable On‐Paper Arrays

Advanced Sensor Research, EarlyView.
This perspective highlights the emerging role of pattern‐recognition, printable on‐paper sensor arrays for intelligent PoC diagnostics. It discusses how paper's inherent limitations can be overcome through surface modification and scalable printing, and how machine‐learning analysis of cross‐reactive arrays enables multiplexed, low‐cost, and REASSURED ...
Naimeh Naseri, Saba Ranjbar
wiley   +1 more source

Trends in LDL-C following coronary angiography involving assessment by fractional flow reserve in obstructive vs non-obstructive coronary artery disease

, 2023
Michael J. Wilkinson, Irvin Xu, Rajiv S. Vasudevan, Hyeri You, Ronghui Xu, Pam R. Taub   +5 more
openalex   +1 more source

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Evaluation of Significant Coronary Artery Disease Based on CT Fractional Flow Reserve and Plaque Characteristics Using Random Forest Analysis in Machine Learning [PDF]

, 2020
Tomohiro Kawasaki, Masafumi Kidoh, Teruhito Kido, Daisuke Sueta, Shinichiro Fujimoto, Kanako K. Kumamaru, Teruyoshi Uetani, Yuki Tanabe, Toshio Ueda, Daisuke Sakabe, Seitaro Oda, Tsuneo Yamashiro, Kenichi Tsujita, Shingo Kato, Hideaki Yuki, Daisuke Utsunomiya   +15 more
openalex   +1 more source