ECGDetect: Detecting Ischemia via Deep Learning [PDF]
Coronary artery disease(CAD) is the most common type of heart disease and the leading cause of death worldwide[1]. A progressive state of this disease marked by plaque rupture and clot formation in the coronary arteries, also known as an acute coronary syndrome (ACS), is a condition of the heart associated with sudden, reduced blood flow caused due to ...
arxiv
Estrogen plus progestin and the risk of coronary heart disease.
BACKGROUND Recent randomized clinical trials have suggested that estrogen plus progestin does not confer cardiac protection and may increase the risk of coronary heart disease (CHD).
J. Manson+14 more
semanticscholar +1 more source
This study reveals a novel crosstalk between hepatic SREBP2‐mediated cholesterol biosynthesis pathway and peripheral lipoprotein lipase‐mediated lipolysis pathway in the regulation of systemic lipid metabolism. Notably, the lipid‐lowering effects of SREBP2 inhibition are independent of a functional LDL receptor, highlighting the potential of acute ...
Yifan Wang+13 more
wiley +1 more source
The Effect of Waist Circumferences More Than Normal on the Incident of Coronary Heart Disease [PDF]
Introduction: Coronary heart disease is known as the most common disease that causes mortality in the world, one of the examination to identify the risks of coronary heart disease is measuring waist circumference.
Hidayati, R. (Ratna), Wahyu, P. (Pria)
core
Coronary heart disease, chronic inflammation, and pathogenic social hierarchy: a biological limit to possible reductions in morbidity and mortality [PDF]
We suggest that a particular form of social hierarchy, which we characterize as 'pathogenic', can, from the earliest stages of life, exert a formal analog to evolutionary selection pressure, literally writing a permanent developmental image of itself upon immune function as chronic vascular inflammation and its consequences.
arxiv
Genomic prediction of coronary heart disease
Background Genetics plays an important role in coronary heart disease (CHD) but the clinical utility of a genomic risk score (GRS) relative to clinical risk scores, such as the Framingham Risk Score (FRS), is unclear. Methods We generated a GRS of 49,310
Gad Abraham+14 more
semanticscholar +1 more source
Cubic Phase‐Inducible Zwitterionic Phospholipids Improve the Functional Delivery of mRNA
In this study, a chemically engineered zwitterionic phospholipids derived from 1,2‐dioleoyl‐3‐sn‐glycero‐phosphoethanolamine (DOPE), DOPE‐Cx, are designed. The DOPE‐Cx lipids induce a cubic phase upon mixing with phosphatidylcholine, facilitate membrane fusion‐mediated endosomal escape, and enhance the functional delivery of mRNA.
Kazuki Iwakawa+5 more
wiley +1 more source
Penyakit Periodontal Sebagai Penyebab Penyakit Jantung Koroner Di Rsup Dr. Kariadi Semarang [PDF]
Background: Cardiovascular disease is a prevalent disease that occured on human population in this world. This disease was in second position in the most deadly disease after infection.
Hanum, F. (Farichah)+3 more
core
Implementation of Bayes Theorem in Expert System to Diagnose Coronary Heart Disease [PDF]
Coronary heart disease is a heart disease that involves disorders of the blood vessels (coronary arteries). Recognizing and treating them requires attention and recognition of existing risk factors.
Hasugian, Penda Sudarto+1 more
core +2 more sources
Do patients with suspected heart failure and preserved left ventricular systolic function suffer from "diastolic heart failure" or from misdiagnosis? A prospective descriptive study [PDF]
OBJECTIVES: To characterise the clinical features of patients with suspected heart failure but preserved left ventricular systolic function to determine if they have other potential causes for their symptoms rather than being diagnosed with 'diastolic ...
Caruana, L.+3 more
core +2 more sources