Results 151 to 160 of about 1,922,582 (395)

Prognostic value of serum glycated albumin in acute coronary syndrome patients without standard modifiable cardiovascular risk factors

open access: yesDiabetology & Metabolic Syndrome
Background Glycated albumin (GA) has been demonstrated to be associated with adverse outcomes in patients with acute coronary syndrome (ACS). However, as a specific subgroup of ACS, a significant proportion of patients with ACS without standard ...
Xiaoming Zhang   +5 more
doaj   +1 more source

Development and Validation of Machine Learning‐Based Marker for Early Detection and Prognosis Stratification of Nonalcoholic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao   +14 more
wiley   +1 more source

The combinational effect of cardiac and biochemical markers in diabetic patients with cardiovascular disease [PDF]

open access: yes, 2011
Background: Clinicopathological correlations, as well as several angiographic studies, suggest that diabetic patients have more extensive atherosclerotic disease, affecting the coronary arteries in particular.
Palanisamy Pasupathi, YY Rao, Farook J, Sathiyamoorthy Subramaniyam, Babu Shankar Ponnusha, Athimoolam Ambika, Int J Cur Bio Med Sci.
core  

Chronic Psychological Stress Induces Cardiomyocyte Hypertrophy Through Corticosterone‐Glucocorticoid Receptor‐LAMA5 Axis

open access: yesAdvanced Science, EarlyView.
In vivo experiments suggest that cardiomyocyte hypertrophy is an early manifestation of cardiac pathological changes induced by chronic psychological stress. In vivo and in vitro experiments suggest that the corticosterone‐glucocorticoid receptor‐LAMA5 axis mediates cardiomyocyte hypertrophy induced by chronic psychological stress. The clinical results
Chuanjing Zhang   +10 more
wiley   +1 more source

Prediction of coronary heart disease using risk factor categories.

open access: yesCirculation, 1998
P. Wilson   +5 more
semanticscholar   +1 more source

Metabolic Stress‐Induced Choline Kinase α (CHKA) Activation in Endothelial Subpopulation Contributes to Diabetes‐Associated Microvascular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren   +11 more
wiley   +1 more source

Tumor Extracellular Vesicles Aggravate Mitochondrial Damage in Myocardial Ischemia/Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
This study reveals a novel mechanistic connection between cancer and ischemia/reperfusion (I/R)‐induced cardiac injury. The meta‐analysis demonstrates significantly higher incidence ratios of both all‐cause mortality and cardiovascular mortality in cancer patients undergoing percutaneous coronary intervention (PCI) compared to non‐cancer patients.
Zhongting Mei   +14 more
wiley   +1 more source

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