Results 21 to 30 of about 549,653 (268)
Background It has been demonstrated that glycated albumin (GA) is significantly associated with diabetes complications and mortality. However, among patients diagnosed with non-ST-elevation acute coronary syndrome (NSTE-ACS) administered percutaneous ...
Chi Liu +7 more
doaj +1 more source
Background Measurement of estimated glucose disposal rate (eGDR) has been demonstrated to be an indicator of insulin resistance (IR) and a risk sign for long-term outcomes in those with ischemic heart disease and type 2 diabetes mellitus (T2DM) having ...
Chi Liu +7 more
doaj +1 more source
The genetics of coronary heart disease [PDF]
Coronary heart disease (CHD) is a leading cause of death worldwide, yet many areas of its pathogenesis remain unknown or poorly understood, leaving potential for novel preventive and therapeutic interventions. Recent major advances in genomic science and technology have opened new avenues of investigation in the pathogenesis of CHD, some of which are ...
Daniel I, Swerdlow +3 more
openaire +2 more sources
Hypertension and coronary heart disease [PDF]
The association of hypertension and coronary heart disease is a frequent one. There are several pathophysiologic mechanisms which link both diseases. Hypertension induces endothelial dysfunction, exacerbates the atherosclerotic process and it contributes to make the atherosclerotic plaque more unstable.
openaire +3 more sources
Background Insulin resistance (IR), evaluation of which is difficult and complex, is closely associated with cardiovascular disease. Recently, various IR surrogates have been proposed and proved to be highly correlated with IR assessed by the gold ...
Qi Zhao +6 more
doaj +1 more source
Although oxidative stress (OS) links to the pathogenesis of coronary artery disease (CAD), its underlying genetic mechanisms remain unclear. Through summary data–based Mendelian randomization (SMR) and colocalization, this research seeks to assess the ...
Hongliang Zhang +9 more
doaj +1 more source
Background The association between mean platelet volume (MPV) and coronary plaque vulnerability in patients with non-ST-elevation ACS (NSTE-ACS) has not been investigated.
Jun Wang +7 more
doaj +1 more source
Background Dyslipidemia is a key driver of coronary artery disease (CAD) development. This study aimed to determine whether the atherogenic index of plasma (AIP), a novel comprehensive lipid index, is an independent and reliable predictor of CAD risk in ...
Qianyun Guo +7 more
doaj +1 more source
Regeneration of the heart: from molecular mechanisms to clinical therapeutics
Heart injury such as myocardial infarction leads to cardiomyocyte loss, fibrotic tissue deposition, and scar formation. These changes reduce cardiac contractility, resulting in heart failure, which causes a huge public health burden.
Qian-Yun Guo +3 more
doaj +1 more source
BackgroundTriglyceride-glucose (TyG) index, a novel surrogate marker of insulin resistance, has been demonstrated to be significantly associated with cardiovascular disease.
Zi-Wei Zhao +6 more
doaj +1 more source

