Results 21 to 30 of about 549,653 (268)

Prognostic implication of serum glycated albumin for patients with non-ST-segment elevation acute coronary syndrome undergoing percutaneous coronary intervention

open access: yesCardiovascular Diabetology, 2022
Background It has been demonstrated that glycated albumin (GA) is significantly associated with diabetes complications and mortality. However, among patients diagnosed with non-ST-elevation acute coronary syndrome (NSTE-ACS) administered percutaneous ...
Chi Liu   +7 more
doaj   +1 more source

Predictive worth of estimated glucose disposal rate: evaluation in patients with non-ST-segment elevation acute coronary syndrome and non-diabetic patients after percutaneous coronary intervention

open access: yesDiabetology & Metabolic Syndrome, 2022
Background Measurement of estimated glucose disposal rate (eGDR) has been demonstrated to be an indicator of insulin resistance (IR) and a risk sign for long-term outcomes in those with ischemic heart disease and type 2 diabetes mellitus (T2DM) having ...
Chi Liu   +7 more
doaj   +1 more source

The genetics of coronary heart disease [PDF]

open access: yesBritish Medical Bulletin, 2012
Coronary heart disease (CHD) is a leading cause of death worldwide, yet many areas of its pathogenesis remain unknown or poorly understood, leaving potential for novel preventive and therapeutic interventions. Recent major advances in genomic science and technology have opened new avenues of investigation in the pathogenesis of CHD, some of which are ...
Daniel I, Swerdlow   +3 more
openaire   +2 more sources

Hypertension and coronary heart disease [PDF]

open access: yesJournal of Human Hypertension, 2002
The association of hypertension and coronary heart disease is a frequent one. There are several pathophysiologic mechanisms which link both diseases. Hypertension induces endothelial dysfunction, exacerbates the atherosclerotic process and it contributes to make the atherosclerotic plaque more unstable.
openaire   +3 more sources

Comparison of various insulin resistance surrogates on prognostic prediction and stratification following percutaneous coronary intervention in patients with and without type 2 diabetes mellitus

open access: yesCardiovascular Diabetology, 2021
Background Insulin resistance (IR), evaluation of which is difficult and complex, is closely associated with cardiovascular disease. Recently, various IR surrogates have been proposed and proved to be highly correlated with IR assessed by the gold ...
Qi Zhao   +6 more
doaj   +1 more source

Oxidative Stress–Related Genome-Wide Mendelian Randomization Identifies Causal Genes for Coronary Artery Disease

open access: yesCardiovascular Therapeutics
Although oxidative stress (OS) links to the pathogenesis of coronary artery disease (CAD), its underlying genetic mechanisms remain unclear. Through summary data–based Mendelian randomization (SMR) and colocalization, this research seeks to assess the ...
Hongliang Zhang   +9 more
doaj   +1 more source

Mean platelet volume and coronary plaque vulnerability: an optical coherence tomography study in patients with non-ST-elevation acute coronary syndrome

open access: yesBMC Cardiovascular Disorders, 2019
Background The association between mean platelet volume (MPV) and coronary plaque vulnerability in patients with non-ST-elevation ACS (NSTE-ACS) has not been investigated.
Jun Wang   +7 more
doaj   +1 more source

The sensibility of the new blood lipid indicator——atherogenic index of plasma (AIP) in menopausal women with coronary artery disease

open access: yesLipids in Health and Disease, 2020
Background Dyslipidemia is a key driver of coronary artery disease (CAD) development. This study aimed to determine whether the atherogenic index of plasma (AIP), a novel comprehensive lipid index, is an independent and reliable predictor of CAD risk in ...
Qianyun Guo   +7 more
doaj   +1 more source

Regeneration of the heart: from molecular mechanisms to clinical therapeutics

open access: yesMilitary Medical Research, 2023
Heart injury such as myocardial infarction leads to cardiomyocyte loss, fibrotic tissue deposition, and scar formation. These changes reduce cardiac contractility, resulting in heart failure, which causes a huge public health burden.
Qian-Yun Guo   +3 more
doaj   +1 more source

Triglyceride-glucose index and non-culprit coronary plaque characteristics assessed by optical coherence tomography in patients following acute coronary syndrome: A cross-sectional study

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundTriglyceride-glucose (TyG) index, a novel surrogate marker of insulin resistance, has been demonstrated to be significantly associated with cardiovascular disease.
Zi-Wei Zhao   +6 more
doaj   +1 more source

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