Results 81 to 90 of about 97,579 (254)

Murray Law–Based Quantitative Flow Ratio Proficiency in Clinical Practice: Validating Routine Diagnostic Performance and Analyzing Learning Curve Thresholds

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Although second‐generation Murray law–based quantitative flow ratio uses artificial intelligence–driven automation to improve angiography‐derived physiological assessment, the impact of operator learning curves on its diagnostic reliability in
Dan Deng, Yue Feng, Min Zeng, Shuhui Chen, Haoran Qin, Yanxiu Chen, Lihua Li, Jianfang Zhu, Chen Wan, Hao Gao, Feng Liu, Dali Yi, Wanchun Luo, William Kongto Hau, Shengxian Tu, Zhihui Zhang   +15 more
doaj   +1 more source

Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation

Advanced Science, EarlyView.
Dynamic supramolecular assembly reshapes targeted protein degradation by coordinating modular degrader construction, delivery, functional integration, and intracellular assembly or activation across proteasomal, endosomal–lysosomal, and autophagy–lysosomal pathways.
Kongjun Liu, Xue Yuan, Yan Zhou, Rui Yuan, Shaocheng Xie, Yong Chen, Peiyi Wang, Jianmei Gao, Qihai Gong   +8 more
wiley   +1 more source

Coronary Physiology

JACC: Cardiovascular Imaging, 2020
Nils P. Johnson, K. Lance Gould
openaire   +1 more source

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

Advanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim, Minju Lee, Yiming Wang, Eunjin Choi, Ji Sun Park, Kyungmin Park, Hayoung Jeon, Donghyun Kim, Donghyun Lee, Yeeun Lee, Kee‐Pyo Kim, Eunha Kim, Heebeom Koo   +12 more
wiley   +1 more source

Primary antiphospholipid syndrome complicated by recurrent acute ST-elevation myocardial infarction: a case report

Frontiers in Cardiovascular Medicine
Clinical management of primary antiphospholipid syndrome (PAPS) complicated by acute myocardial infarction (AMI) is particularly challenging, especially when recurrent AMI and thrombocytopenia are present.
Liming Huo, Chang Hou, Chengfu Cao, Xin Peng, Jian Liu   +4 more
doaj   +1 more source

Physiology of Coronary Microcirculation

, 2022
info:eu-repo/semantics ...
Jacinto, S, Morais, L
openaire   +1 more source

Freestanding Hierarchical‐Porous BCZT Thin Films Enable Efficient Ultrasonic Energy Harvesting in Soft Tissue

Advanced Science, EarlyView.
Freestanding hierarchical‐porous BCZT thin films integrate a compliant porous surface with a dense piezoceramic backbone to balance mechanical reliability, voltage sensitivity, and acoustic coupling. The films enable stable wearable pulse‐wave monitoring and enhanced tissue‐coupled ultrasonic energy harvesting, offering a promising route toward soft ...
Zifan Li, Shengwei Gao, Wang Hong, Yuxin Chen, Yiyang Gu, Xu Wang, Chen Tang, Ying Hong, Xuemu Li, Xiaodong Yan, Yi Zheng, Yiming Liu, Junchen Liao, Biao Wang, Shiyuan Liu   +14 more
wiley   +1 more source

Percutaneous coronary intervention in cardiac allograft vasculopathy: From lesion selection to longitudinal graft management

JHLT Open
Cardiac allograft vasculopathy remains a major cause of late graft dysfunction and mortality after heart transplantation. Percutaneous coronary intervention can treat focal epicardial disease, but its role is complicated by diffuse epicardial involvement,
Ajay Dharan, MD, Muhammed Faraz Ali, Nalin Dayawansa, MBBS, PhD, Sarah Gutman, MBBS, PhD, Hitesh Patel, MBBS Bsc, PhD, David M. Kaye, MBBS, PhD, James A. Shaw, Assoc. Professor, MBBS, PhD   +6 more
doaj   +1 more source

THSD7A Exacerbates Atherosclerosis via Activation of Signaling Axis αvβ3/CEBPD/IL1A

Advanced Science, EarlyView.
THSD7A exerts pro‐inflammatory effects and exacerbates atherosclerosis. Mechanistically, THSD7A regulates endothelial cell inflammation and atherosclerosis by activating the αvβ3/CEBPD/IL1A signaling axis. THSD7A is not only a genetic marker but also a potential therapeutic target for coronary artery disease (CAD).
Jiankun Liu, Hongfei Liu, Yiqi Wan, Andong Wu, Jiayu Qiu, Xueting Gong, Ya Zhao, Yuanyuan Li, Bingbing Zhou, Yangyi Zheng, Fang Wu, Yuanzheng Zhu, Weixin Lv, Xueer Li, Qiang Yuan, Xiao‐Li Tian   +15 more
wiley   +1 more source

Update in Coronary Physiology

Indian Journal of Cardiovascular Disease in Women
Physiological assessment of coronary artery disease plays a key role in guiding myocardial revascularization, with robust evidence backing the use of fractional flow reserve (FFR) and other pressure-based indexes. Angiography has its limitations in the assessment of the severity of lesions.
Maria Jyothi F. B., Girish B. Navasundi, Johann Christopher   +2 more
openaire   +1 more source