Results 111 to 120 of about 796,466 (237)
Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2
Advanced Science, EarlyView.Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang +15 more
wiley +1 more source
Closing the Loop: High‐Precision 3D Photofabrication in Living Tissues
Advanced Science, EarlyView.Writing 3D microstructures inside living tissue demands more than laser access; It demands information. Hierarchical sensing captures thermal and mechanical states across pulse‐train, voxel, and structure timescales, feeding a controller that steers the laser in real time.
Amirbahador Zeynali +2 more
wiley +1 more source
Federal reserve inter-district collection system /
Description based on: June 1, 1917."Changes in list of banks upon which items will be received by federal reserve banks for collection and credit" (varies slightly).Mode of access: Internet.Issued 1916-1935 by the Federal Reserve Board; issued 1936 ...
United States. Federal Reserve Board. +1 more
core
Decreased coronary vascular reserve in Watanabe heritable hyperlipidemic rabbits.
, 1988 Watanabe heritable hyperlipidemic (WHHL) rabbits have severe hypercholesterolemia due to a genetic defect in their low density lipoprotein receptors. Therefore, they develop severe premature atherosclerosis of the large arteries including the coronary ...
H R Baumgartner +3 more
core +1 more source
The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ
Advanced Science, EarlyView.UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi +6 more
wiley +1 more source
Effect of sodium-glucose Co-transporter 2 inhibitors on coronary microcirculation
Frontiers in PharmacologyCoronary microvascular disease (CMVD) has emerged as a new target for the occurrence and development of heart failure treatment. Various indicators such as Index of Microvascular Resistance, Coronary Flow Reserve, Microvascular Resistance Reserve ...
Shaoxin Chen +5 more
doaj +1 more source
Coronary transport reserve in normal dogs
, 1984 This study was designed to determine an acceptable method for producing maximal coronary vasodilation for quantifying coronary blood flow reserve and coronary capillary transport reserve.
M. H. Laughlin
core +1 more source
A Facial Foundation Model for Clinical Biomarker Prediction and Real‐World Mobile Deployment
Advanced Science, EarlyView.MedicalFaceFound is a facial foundation model developed through three‐stage progressive pre‐training, adapting representations from general vision to facial structure and clinical phenotypes. Using a single facial image, it estimates 62 biomarkers across multiple physiological systems and supports downstream risk prediction for cardiovascular ...
Tingfeng Xu +15 more
wiley +1 more source
General, account of John Barr of early settlers in the Western Reserve, including biographical sketches, a chronology, and notes on the towns of Mayfield Brecksville, Solon, and Rockport, 1846?Cleveland, Ohio and the Western Reserve Digital Text ...
Barr, John (Creatorcre)
core
, 2007 Aims. The aim of this study was to evaluate whether assessment of coronary flow velocity (CFV) and coronary flow reserve (CFR) in left anterior descending coronary artery (LAD) by transthoracic Doppler echocardiography (TTDE) adds diagnostic information ...
VITARELLI, Antonino +10 more
core