Results 111 to 120 of about 120,121 (213)

Polypropylene Nanoplastic Exposure to Respiratory Epithelial Barrier‐On‐Chip and Interfacial Interactions With Human Serum Albumin

open access: yesAllergy, EarlyView.
Exposure to 305 nm PP NPs significantly disrupts the airway barrier‐on‐chip, reducing TEER, suppressing ZO‐1/ACE2 expression, and triggering ROS‐mediated apoptosis. In biological media, PP NPs exhibit a biphasic adsorption pattern, leading to the formation of a protein corona that increases their size to 364 nm.
Omur Sert   +9 more
wiley   +1 more source

Post‐Market Analysis of the Xenios Console With the Xlung Tubing Kit 230 for Extracorporeal Membrane Oxygenation After Cardiac Surgery

open access: yesArtificial Organs, EarlyView.
This study is a comprehensive post‐market analysis of the Xenios console and XLung kit 230 preconfigured ECMO tubing set in post‐cardiotomy applications. The performance of this device was evaluated and demonstrated in all key clinical areas, with an adequate safety profile.
Luca Conci   +9 more
wiley   +1 more source

An Optimized Multi‐Stage Drainage Cannula Design for Venoarterial Extracorporeal Membrane Oxygenation

open access: yesArtificial Organs, EarlyView.
This study utilized an extensive optimization involving n = 540 design of experiments to produce a superior drainage cannula design. Compared to the clinically used Maquet model, our optimized design demonstrated reduced blood stagnation volumes, increased cannula tip velocities, and higher upper body drainage, potentially minimizing risk of thrombosis
Avishka Wickramarachchi   +3 more
wiley   +1 more source

COVID-19 patient with coronary thrombosis supported with ECMO and Impella 5.0 ventricular assist device: a case report. [PDF]

open access: yesEur Heart J Case Rep, 2020
Valchanov K   +9 more
europepmc   +1 more source

SURGELLA: A Scoping Review of Impella‐Assisted Hemodynamic Support in High‐Risk Non‐Cardiac Surgery

open access: yesArtificial Organs, EarlyView.
In selected patients with severe LV dysfunction, Impella‐supported non‐cardiac surgery may provide a temporary hemodynamic bridge to otherwise prohibitive procedures. Published evidence remains limited to a small number of highly selected cases, supporting technical feasibility rather than comparative benefit or generalizable safety.
Hussein Elghazaly   +6 more
wiley   +1 more source

Clinical Outcomes After Percutaneous Coronary Intervention in Patients With Cirrhosis: A Multicentre National Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Summary of a multicentre TriNetX study evaluating outcomes after percutaneous coronary intervention (PCI) in patients with cirrhosis. Cirrhosis was associated with higher 1‐year gastrointestinal bleeding and mortality, especially with decompensated disease.
Dhir Gala   +13 more
wiley   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

open access: yesBritish Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

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