Results 51 to 60 of about 131,755 (294)

A rare case of spontaneous thrombolysis in a patient with acute myocardial infarction with ST-segment elevation

Acta Medica Leopoliensia, 2018
In the pathogenesis of acute myocardial infarction an important role belongs to coronary sclerosis and coronary artery thrombosis. Endothelium plays an important role in a regulation of vascular tone, local inflammation, hemostasis, neovascularisation ...
Yu.G. Kyyak, M.P. Halkevych, O.Ye. Labinska, O.Yu. Barnett   +3 more
doaj   +1 more source

FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

Advanced Science, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li, Junjian Hu, Suping Hai, Peng Hu, Wenhui Wu, Qiang Gao, Binghui Yu, Feiyang Xu, Xizhe Zheng, Qianting Guan, Huiling Xiang, Dong Xi, Weiming Yan, Peng Wang, Bin‐hao Zhang, Qin Ning, Xiaojing Wang   +16 more
wiley   +1 more source

Great saphenous vein stump: a risk factor for superficial/deep venous thrombosis and an indication for prophylactic anticoagulation? - a retrospective analysis

Journal of Community Hospital Internal Medicine Perspectives, 2019
Background: Great saphenous vein (GSV) grafts are used for coronary artery bypass surgeries, but the remaining stump of the GSV may be the nidus for superficial and deep vein thrombosis.
Yasir Khan, Muhammad Arslan Cheema, Hafez Mohammad Ammar Abdullah, Yasar Sattar, Shujaul Haq, Asoka Balaratna, Khadija Cheema, Waqas Ullah   +7 more
doaj   +1 more source

The optimal treatment of multivessel coronary artery disease [PDF]

, 2014
The practice of percutaneous coronary intervention has overtaken coronary bypass surgery in the treatment of ischaemic heart disease. Several randomized controlled as well as registry and observational trials have addressed the issue of patient selection
Manche, Alexander
core  

Long-term association of routine blood count (Coulter) variables on fatal coronary heart disease: 30-year results from the first prospective Northwick Park Heart Study (NPHS-I).

, 2009
BACKGROUND: Since evidence of a long-term association between routine blood count (Coulter) variables and coronary heart disease (CHD) is inconsistent, the authors analysed white blood cell count (WBC), red blood cell count (RBC), haemoglobin (Hgb ...
De Stavola, Bianca L, Tom W Meade, Bianca L De Stavola, Costanza Pizzi, Pizzi, Costanza, Meade, Tom W   +5 more
core   +1 more source

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

Advanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung   +19 more
wiley   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Impact of antiplatelet therapy on microvascular thrombosis during ST-elevation myocardial infarction

Frontiers in Molecular Biosciences
During an acute coronary syndrome, atherosclerotic plaque rupture triggers platelet activation and thrombus formation, which may completely occlude a coronary artery leading to ST-elevation myocardial infarction (STEMI).
Sophia Khattak, Sophia Khattak, Jonathan N. Townend, Jonathan N. Townend, Mark R. Thomas, Mark R. Thomas   +5 more
doaj   +1 more source

Graft thrombosis after off-pump coronary artery bypass grafting: Postoperative challenges and implications

Journal of the Practice of Cardiovascular Sciences, 2019
Perioperative graft failure is an important cause of myocardial ischemia following coronary artery bypass grafting. Early diagnosis of graft thrombosis is of paramount importance for limiting the sequelae of postoperative myocardial infarction (PMI).
Rohan Magoon, Sambhunath Das, Ameya Karanjkar, Milind P Hote   +3 more
doaj   +1 more source

Biofunctionalization of cardiovascular stents to induce endothelialization: Implications for in- stent thrombosis in diabetes

Frontiers in Pharmacology, 2022
Stent thrombosis remains one of the main causes that lead to vascular stent failure in patients undergoing percutaneous coronary intervention (PCI). Type 2 diabetes mellitus is accompanied by endothelial dysfunction and platelet hyperactivity and is ...
Isra Marei, Isra Marei, Blerina Ahmetaj-Shala, Chris R. Triggle   +3 more
doaj   +1 more source