Results 61 to 70 of about 126,492 (258)

Glycopolymeric nanoparticles transported by activated platelets protect ischemic myocardium by alleviating PANoptosis through targeting macrophage Dectin‐1

BMEMat, EarlyView.
NP‐SF, designed to target macrophage Dectin‐1 and activated platelets, selectively accumulated in ischemic myocardium, where it was taken up by macrophages after platelet hitchhiking. By inhibiting NLRC5‐related PANoptosis, NP‐SF significantly attenuated pathological damage, and effectively preserved cardiac function in a murine ischemia–reperfusion ...
Guanye Yu, Na Yang, Yan Zhang, Lingxin Peng, Yi Li, Yue Chao, Qinfang Miao, Haikun Qi, Jianhui Zhuang, Weixia Jian, Bingyu Li, Wenhui Peng, Jinghua Chen, Shiyu Gong   +13 more
wiley   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Simultaneous Two-Vessel Subacute Stent Thrombosis Caused by Clopidogrel Resistance from CYP2C19 Polymorphism

Case Reports in Medicine, 2016
Clopidogrel resistance from CYP2C19 polymorphism has been associated with stent thrombosis in patients undergoing percutaneous coronary intervention with drug-eluting stents. We present a case of a 76-year-old male who received drug-eluting stents to the
Ashwad Afzal, Bimal Patel, Neel Patel, Sudhakar Sattur, Vinod Patel   +4 more
doaj   +1 more source

Temporal Trends and Prognosis in Rotational Atherectomy: A Comparison of Contemporary and Traditional Eras

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Rotational atherectomy (RA) has undergone considerable technical modernization in recent years. This study evaluated whether RA performed in the contemporary era was associated with superior cardiovascular outcomes compared with the traditional era. Aims To compare the clinical characteristics and cardiovascular outcomes of patients
Ravi Vazirani, Gonzalo García‐Martí, Andrés Provencio‐Regidor, Irene Serrano‐García, Adrián Jerónimo‐Baza, Alejandro Travieso, Gabriela Tirado‐Conte, Fernando Macaya‐Ten, Hernán Mejía‐Rentería, Pablo Salinas, Luis Nombela‐Franco, Pilar Jiménez‐Quevedo, Nieves Gonzalo, Javier Escaned, Antonio Fernández‐Ortiz, Iván J. Núñez‐Gil   +15 more
wiley   +1 more source

Successful Percutaneous Retrieval of an Embolized MitraClip From the Right Subclavian Artery

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Single leaflet device attachment (SLDA) after mitral transcatheter valve edge‐to‐edge repair (M‐TEER) has been reported in up to 5% of patients. However, complete embolization of the M‐TEER device is exceedingly rare. Device retrievals in all previously reported cases were completed by vascular surgery cut down at the end. In this case, we are
Seyed Hossein Aalaei‐Andabili, Diljon S. Chahal, Shahab Tour Savadkohi   +2 more
wiley   +1 more source

Impact of rivaroxaban on stent thrombosis and secondary prevention of cardiovascular events in acute coronary syndrome

Research Reports in Clinical Cardiology, 2014
Marvin Krohn-Grimberghe, Christoph Bode, Constantin von zur MuhlenDepartment of Cardiology and Angiology I, Heart Center, University of Freiburg, GermanyAbstract: Angioplasty and stent implantation have greatly improved the outcome of patients with acute
Krohn-Grimberghe M, Bode C, von zur Muhlen C   +2 more
doaj  

Multivessel coronary artery stenting complicated by stent thrombosis in the setting of hereditary thrombophilia: a clinical case

Рациональная фармакотерапия в кардиологии
An urgent issue remains to determine the role and significance of gene polymorphism encoding components of the blood coagulation and anticoagulation system in increasing the risk of myocardial infarction and its thrombotic complications, including those ...
Z. M. Safiullina, E. M. Mezhonov, S. V. Viatchinina, Yu. A. Vyalkina, A. Kh. Sereshcheva   +4 more
doaj   +1 more source

Novel Use of Intravascular Lithotripsy for the Mobilization of an Entrapped Coronary Guidewire in a Heavily Calcified LAD/DB Bifurcation Lesion—A Case Report

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT A 64‑year‑old man with a Non–ST‑elevation myocardial infarction (NSTEMI) underwent coronary angiography, which revealed single‑vessel disease with a high‑grade proximal and a severely calcified mid‑LAD lesion just proximal to a diagonal branch (DB). Both the LAD and the DB were wired.
Hansmartin Jetter, Jochen Genzel, Wolfram Voelker   +2 more
wiley   +1 more source

Five‐Year Clinical Outcomes of Biodegradable Versus Durable Polymer Drug‐Eluting Stents: A Propensity Score‐Matched Analysis of 4394 Patients

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Biodegradable‐polymer (BP) drug‐eluting stents (DES) were developed to mitigate potential late adverse events related to persistent durable polymers in durable‐polymer (DP) DES; however, contemporary long‐term real‐world comparative data remain limited. Aims We aimed to compare the 5‐year clinical outcomes of contemporary BP‐DES and
Yangyoun Lee, Hong‐Seok Lim, Kyoung‐Woo Seo, Hyoung‐Mo Yang, So‐Yeon Choi, Seung‐Jea Tahk, Myeong‐Ho Yoon   +6 more
wiley   +1 more source

When Subtle Guiding Catheter‐Induced Stent Deformation Leads to Abluminal Guidewire Passage: Successful IVUS Tip‐Detection‐Guided Bailout

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Incomplete stent apposition at the proximal coronary artery may predispose to subtle guiding catheter–induced stent deformation, creating a gap between the stent and the vessel wall that facilitates inadvertent abluminal guidewire passage. We report a case in which balloon dilatation over an unrecognized abluminal guidewire resulted in severe ...
Yuto Abe, Yuya Hirata, Fumimasa Tabata, Tomomi Koizumi   +3 more
wiley   +1 more source