Results 111 to 120 of about 665,831 (247)

Existirá contemporaneidade da medida socioeducativa de internação após a pandemia?

Boletim IBCCRIM
O presente escrito tem como objetivo discutir se a imposição de medida socioeducativa de internação aos adolescentes postos em liberdade no início da pandemia do novo coronavírus respeita os princípios do Estatuto da Criança e do Adolescente. Para tanto,
Adriana Padua Borghi, Ana Paula Cristina Oliveira Freitas   +1 more
doaj  

Influenza em Suínos: situação brasileira e mundial. [PDF]

, 2013
Projeto/Plano de Ação: 02.11.01 ...
ZANELLA, J. R. C.
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Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel, Christine van Linge, W. Joost Wiersinga, Ilse J. E. Kouijzer, Quirijn de Mast, Robert‐Jan Hassing, Danique J. H. Huijbens, Helen L. Leavis, Roger Schutgens, Coen Maas, Kit C. B. Roes, Frank L. van de Veerdonk, Roger Brüggemann   +12 more
wiley   +1 more source

Surfactante pulmonar: avaliação e terapia na bronquiolite viral aguda grave [PDF]

, 2015
Objectives: To evaluate the response to surfactant of patients with acute bronchiolitis (AB) according the surfactant function and production, measured through the stable microbubble test and the lamellar body count.
Hartmann, Francine
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Inflammation‐driven variability in drug metabolism: Insights from voriconazole treatment of HSCT recipients

British Journal of Clinical Pharmacology, EarlyView.
Aims Voriconazole is commonly used to prevent fungal infections after haematopoietic stem cell transplantation (HSCT). Although its metabolism is influenced by CYP2C19 genetics and inflammation, their combined effect is rarely considered in clinical practice, and integrated analyses remain limited.
Sylvia D. Klomp, Martijn L. Manson, Henk‐Jan Guchelaar, Stefan Böhringer, Esther H. M. van Egmond, Peter A. von dem Borne, Jesse J. Swen   +6 more
wiley   +1 more source

Estratégias para aumento da eficiência reprodutiva e produtiva em bovinos de corte. [PDF]

, 2015
Na pecuária de corte, a exploração comercial do sistema de cria se constitui na fase do sistema produtivo, que envolve a criação e o manejo não só das matrizes bovinas e seus respectivos bezerros ate a desmama, mas também das novilhas de reposição e dos ...
ANDREOTTI, R., THIAGO, L. R. L. de S., VALLE, E. R. do   +2 more
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Population pharmacokinetic/pharmacodynamic modelling to evaluate favipiravir in combination with lopinavir–ritonavir in patients with COVID‐19

British Journal of Clinical Pharmacology, EarlyView.
Aims The repurposed use of favipiravir in COVID‐19 has been reported to have limited clinical efficacy, yet it has been widely used in some countries. Favipiravir causes mutagenesis in RNA viruses, and it is currently unknown whether it may have a measurable effect on the virus in humans.
Akosua A. Agyeman, Laura Buggiotti, Li‐An K. Brown, Jose A. Guerra‐Assuncao, Japhette E. Kembou‐Ringert, Wen Y. Mak, Judith Breuer, David M. Lowe, Joseph F. Standing, FLARE Investigators   +9 more
wiley   +1 more source

sanidade avícola contribui para o crescimento da produção de aves. [PDF]

, 2017
Projeto: 11.11.11 ...
ESTEVES, P. A., JAENISCH, F. R. F., TREVISOL, I. M.   +2 more
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RBD‐SD1 Nanoparticle Vaccines From DPP4‐Using Merbecoviruses Elicit a Cross‐Reactive Antibody Response but Limited Cross‐Protective Immunity

Biotechnology and Bioengineering, EarlyView.
SpyCatcher‐mi3 nanoparticles displaying RBD‐SD1 from MERS‐CoV, NL140422, and HKU4 elicited robust and cross‐reactive IgG responses in mice. Only MERS‐CoV RBD‐SD1 induced neutralizing antibodies against MERS‐CoV and protected human DPP4 mice from a MERS‐CoV challenge, indicating conserved serologic but limited cross‐neutralizing epitopes.
Peter J. Halfmann, Jeong Soo Lee, Tong Wang, Augustine Duffy, Janie E. Rogers, Natasha Chen, Elizabeth Frimpong, Carmen Rai, Yoshihiro Kawaoka, Ravi S. Kane   +9 more
wiley   +1 more source

Agrupamento genético de isolados do vírus da bronquite infecciosa das aves no Brasil com base na análise do gene S1 por RT-PCR-RFLP [PDF]

Doze isolados de campo do Brasil e uma estirpe de referência vacinal do vírus da bronquite infecciosa das aves (VBI) foram propagadas em ovos embrionados SPF. O gene S1 dessas amostras foi analisado por RT-PCR seguido de RFLP, empregando-se as enzimas de
BRENTANO, Liana, MONTASSIER, Hélio José, MONTASSIER, Maria de Fátima Silva, RICHTZENHAIN, Leonardo José   +3 more
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