Results 121 to 130 of about 37,384 (259)

Assembly of viral genomes from metagenomes

Frontiers in Microbiology, 2014
Viral infections remain a serious global health issue. Metagenomic approaches are increasingly used in the detection of novel viral pathogens but also to generate complete genomes of uncultivated viruses.
Saskia L Smits, Saskia L Smits, Rogier eBodewes, Aritz eRuiz-Gonzalez, Aritz eRuiz-Gonzalez, Aritz eRuiz-Gonzalez, Wolfgang eBaumgärtner, Marion P Koopmans, Marion P Koopmans, Albert D. M. E Osterhaus, Albert D. M. E Osterhaus, Anita C Schürch   +11 more
doaj   +1 more source

Unveiling Novel Viral Diversity, Biogeography, and Host Networks in Wildlife Through High‐Throughput Sequencing Data Mining

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Hai Wang, Yafei Meng, Xiaoyuan Chen, Xinyuan Cui, Qian Zuo, Na Han, Xianghui Liang, Xuejuan Shen, Caiwu Li, Desheng Li, Fumin Wang, Liangping He, Rujian Chen, Xingbang Lu, Wenjie You, Aiping Wu, Rui‐Ai Chen, Wu Chen, Chan Ding, Yongyi Shen   +19 more
wiley   +1 more source

Neonatal foal death due to infection with equine arteritis virus in Belgium [PDF]

, 2009
This case report describes a small outbreak of neonatal foal death in Belgium due to infection with equine arteritis virus (EAV). The outbreak started with one foal suffering from acute dyspnea four days after birth.
Chiers, Koen, Ducatelle, Richard, Govaere, Jan, Gryspeerdt, Annick, Nauwynck, Hans, Van de Walle, Gerlinde, Vercauteren, Griet   +6 more
core  

Exploring Plant‐Derived Nutraceuticals as Potential SARS CoV‐2 Mpro Inhibitors

Food Chemistry International, Volume 1, Issue 4, Page 492-496, December 2025.
The search for plant derived anti‐SARS‐CoV‐2 Mpro compounds starts from food plants and spices as rich sources of bioactive compounds. Both in silico screening and experimental validation are essential to assess their therapeutic potential, leading to candidates for drug development and dietary integration.
Shaza S. Issa, Tatiana V. Matveeva
wiley   +1 more source

A New Bat-HKU2–like Coronavirus in Swine, China, 2017

Emerging Infectious Diseases, 2017
We identified from suckling piglets with diarrhea in China a new bat-HKU2–like porcine coronavirus (porcine enteric alphacoronavirus). The GDS04 strain of this coronavirus shares high aa identities (>90%) with the reported bat-HKU2 strains in ...
Lang Gong, Jie Li, Qingfeng Zhou, Zhichao Xu, Li Chen, Yun Zhang, Chunyi Xue, Zhifen Wen, Yongchang Cao   +8 more
doaj   +1 more source

The Human Respiratory Virome in Health and Disease: Interactions, Dysbiosis, and Methodological Challenges

Advanced Genetics, Volume 6, Issue 4, December 2025.
This article examines how the respiratory virome contributes to health and disease, highlighting its interactions with the host and bacteriome. Key disease associations and present knowledge gaps are outlined. The review discusses challenges in sample collection and preprocessing, and presents future research directions for understanding virome ...
Xiaoxuan Yao, Xiaohui Zou, Bin Cao
wiley   +1 more source

Five‐Year (2017–2022) Evolutionary Dynamics of Human Coronavirus OC43 in Southern France Based on Whole Genome Next‐Generation Sequencing

Journal of Medical Virology, Volume 97, Issue 12, December 2025.
ABSTRACT HCoV‐OC43 genomes and their evolution are scarcely studied worldwide and in France, with only 361 genomes available as of October 2023. Here, an in‐house PCR amplification system was implemented to obtain retrospectively by next‐generation sequencing, then analyze HCoV‐OC43 genomes for infections diagnosed with this virus in southern France ...
Hikmat Houmadi, Céline Boschi, Marine Lefebvre, Lorlane Le Targa, Justine Py, Jean‐Christophe Lagier, Lucile Lesage, Jacques Fantini, Aurélie Morand, Bernard La Scola, Philippe Colson   +10 more
wiley   +1 more source

Novel hemotropic mycoplasmas are widespread and genetically diverse in vampire bats [PDF]

, 2017
Bats (Order: Chiroptera) have been widely studied as reservoir hosts for viruses of concern for human and animal health. However, whether bats are equally competent hosts of non-viral pathogens such as bacteria remains an important open question. Here,
Altizer, S.M., Becker, D.J., Bergner, L.M., Camus, M.S., Chizhikov, V.E., Orton, R.J., Streicker, D.G., Volokhov, D.V.   +7 more
core   +1 more source

Role of the DPP4 Receptor in SARS‐CoV Entry: Insights From Docking and Molecular Dynamics Simulations

Proteins: Structure, Function, and Bioinformatics, Volume 93, Issue 12, Page 2091-2100, December 2025.
ABSTRACT Protein–receptor interactions play a critical role in viral entry and pathogenesis. While ACE2 is the primary receptor for SARS‐CoV, the role of DPP4 as potential coreceptor remains underexplored. This study investigates the binding mechanisms and dissociation dynamics of the SARS‐CoV/DPP4, SARS‐CoV/ACE2 and MERS‐CoV/DPP4 complexes using ...
Patrícia Pereira Duzi Carvalho, Nelson Augusto Alves   +1 more
wiley   +1 more source

Improved vaccine strategies of infectious bronchitis disease to reduce shedding of virulent virus from infected birds

Kufa Journal for Veterinary Medical Sciences, 2017
Infectious bronchitis (IB) threatens the economies of entire nations, by adversely affecting the backyard farmers, poultry producers and poultry industry throughout the world.
Mushtaq T. B. AL-Zuhariy
doaj   +1 more source