Results 131 to 140 of about 264,219 (265)

Meeting the Psychological Needs of People Recovering from Severe Coronavirus

, 2020
This guidance considers the likely psychological needs of people who have been hospitalised with severe coronavirus (Covid-19), and the most effective ways to support their ...
Paul, Twose, Wade, Dorothy, Doyle, Ann Marie, Moss-Morris, Rona, Dupont, Simon, Frizelle, Dorothy, Bunnage, Martin, Firschman, Penny, Morrison, Val, Fish, Jessica, Murray, Hannah, Murphy, David   +11 more
core  

A phase 1 study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of PF‐07261271 in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim There is an unmet need for more effective therapies in inflammatory bowel disease (IBD). A single drug that blocks multiple distinct pathogenic pathways may offer therapeutic benefit superior to current monotherapies. PF‐07261271, a bispecific antibody targeting both the p40 subunit of interleukin‐12/23 and tumour necrosis factor‐like cytokine 1A ...
Srividya Neelakantan, Christopher Banfield, Kenneth Hung, Anna Sapone, Vivek Pradhan, Yuxi Zhao, Dana Parsons‐Rich, Grace Lee, Bryce G. Johnson, Elena Peeva, Michael S. Vincent, Valerie M. Clerin   +11 more
wiley   +1 more source

Risk of venous thromboembolism after SARS‐CoV‐2 vaccination—Evidence from genome‐wide association study and population‐based observational study

British Journal of Clinical Pharmacology, EarlyView.
Aim We aimed to investigate whether genetic variation is associated with venous thromboembolism after immunization with SARS‐CoV‐2 vaccines. Methods We conducted a genome‐wide association study (GWAS) on cases of venous thromboembolism within 42 days after SARS‐CoV‐2 vaccination, recruited from reports of adverse drug reactions sent to the Swedish ...
Sofia Attelind, Niclas Eriksson, Marco Cavalli, Yiyi Xu, Fredrik Nyberg, Anders Sundström, Mia Wadelius, Pär Hallberg   +7 more
wiley   +1 more source

Guidance for preventive and responsive measures to coronavirus by police and law enforcement

, 2020
The coronavirus, or COVID-19, has already been declared by the World Health Organization as a global pandemic. As the number of people infected in the United States grows exponentially, we must focus on prevention and containment in the criminal and ...
Vera Institute of Justice
core  

S. aureus colonization and clinical symptoms remain stable upon topical XZ.700 treatment: Results of a double‐blind randomized clinical trial in patients with mild to moderate atopic dermatitis

British Journal of Clinical Pharmacology, EarlyView.
Aim Recovering dysbiosis may improve atopic dermatitis (AD) symptoms. XZ.700 is a recombinant chimeric endolysin that specifically targets Staphylococcus aureus and could be a new treatment option for patients with AD. The aim of this first‐in‐human study was to evaluate the safety, tolerability and efficacy of topical XZ.700 and explore the ...
Laura W. J. van der Meulen, Menthe E. Bergmans, Salma Assil, Naomi Klarenbeek, Marieke L. de Kam, Alexa J. Tibboel, Thorsten Brach, Bjorn L. Herpers, Johan Frieling, Vincent de Jong, Benthe Freyee, Martijn B. A. van Doorn, Robert Rissmann, Tessa Niemeyer–van der Kolk   +13 more
wiley   +1 more source

Guidance for preventive and responsive measures to coronavirus for youth agencies

, 2020
The coronavirus, or COVID-19, has been declared by the World Health Organization to be a global pandemic. As the number of people infected in the United States grows exponentially, we must focus on prevention and containment in the criminal and ...
Vera Institute of Justice
core  

Estimating the human health risk from possible BSE infection of the British sheep flock.

, 2002
Following the controversial failure of a recent study and the small numbers of animals yet screened for infection, it remains uncertain whether bovine spongiform encephalopathy (BSE) was transmitted to sheep in the past via feed supplements and whether ...
T. J. Hagenaars, Donnelly, CA, Ghani, AC, Anderson, RM, Ferguson, NM, A. C. Ghani, Hagenaars, TJ, C. A. Donnelly, R. M. Anderson, N. M. Ferguson   +9 more
core   +1 more source

Toward clone‐on‐a‐chip: Ethical and legal considerations for organ‐on‐a‐chip evolution

BMEMat, EarlyView.
The term “clone‐on‐a‐chip (CoC)” is introduced as a conceptual warning for personalized organ‐on‐a‐chip platforms and not to suggest technological feasibility, where a CoC ethical discussion extends beyond issues arising from the requirements for informed consent, property rights, commercialization efforts, and cell sourcing to include potentially ...
Muhammed Erkan Karabekmez, Aliakbar Ebrahimi, Hamed Ghorbanpoor, Nicole Bassous, Su Ryon Shin, Yu Shrike Zhang, Huseyin Avci   +6 more
wiley   +1 more source

Guidance for preventive and responsive measures to coronavirus for parole, probation, and clemency

, 2020
The coronavirus, or COVID-19, has already been declared by the World Health Organization as a global pandemic. As the number of people infected in the United States grows exponentially, we must focus on prevention and containment in the criminal and ...
Vera Institute of Justice
core  

Methods for estimating the case fatality ratio for a novel, emerging infectious disease.

, 2005
During the course of an epidemic of a potentially fatal disease, it is important that the case fatality ratio be well estimated. The authors propose a novel method for doing so based on the Kaplan-Meier survival procedure, jointly considering two ...
W. S. Chan, A. J. Hedley, Donnelly, CA, T. H. Lam, Hedley, AJ, A. C. Ghani, L. M. Ho, C. A. Donnelly, D. R. Cox, C. Fraser, G. M. Leung, Ho, LM, Ghani, AC, Anderson, RM, Cox, DR, Lam, TH, Griffin, JT, Leung, GM, Fraser, C, Chan, WS, J. T. Griffin, R. M. Anderson   +21 more
core   +1 more source