Results 171 to 180 of about 1,253,166 (338)

Oligonucleotide separation techniques for purification and analysis: What can we learn for today's tasks?

open access: yesELECTROPHORESIS, Volume 43, Issue 23-24, Page 2402-2427, December 2022., 2022
Abstract Nucleic acids are the blueprint of life. They are not only the construction plan of the single cell or higher associations of them, but also necessary for function, communication and regulation. Due to the pandemic, the attention shifted in particular to their therapeutic potential as a vaccine. As pharmaceutical oligonucleotides are unique in
Robert Minkner   +3 more
wiley   +1 more source

Recent advances and challenges in temperature monitoring and control in microfluidic devices

open access: yesELECTROPHORESIS, Volume 44, Issue 1-2, Page 268-297, January 2023., 2023
Abstract Temperature is a critical—yet sometimes overlooked—parameter in microfluidics. Microfluidic devices can experience heating inside their channels during operation due to underlying physicochemical phenomena occurring therein. Such heating, whether required or not, must be monitored to ensure adequate device operation.
Alejandro A. Dos‐Reis‐Delgado   +6 more
wiley   +1 more source

Comparison of the pathogenicity and neutrophil and monocyte response between SARS‐CoV‐2 prototype and Omicron BA.1 in a lethal mouse model

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We conducted clinical characterization studies and performed virological evaluations on mice infected with SARS‐CoV‐2 prototype and Omicron BA.1 using RT‐PCR, HE and immunohistochemistry staining. We also studied the alterations of neutrophils and monocytes caused by the two strains using complete blood count, immunohistochemistry, and flow cytometry ...
Na Rong   +8 more
wiley   +1 more source

Antiviral effects and mechanism of Qi pi pill against influenza viruses

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Qi pi pill presents anti‐influenza effect and inhibits viral replication in vitro by targeting both the viral RNA replication and the release of new viral particles. Furthermore, QPP modulates the production of proinflammatory cytokines induced by influenza infection in host cells.
Chengcheng Zhang   +10 more
wiley   +1 more source

Progress in research on osteoporosis secondary to SARS‐CoV‐2 infection

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This review explores the potential mechanisms, complications, risk factors, and future research directions related to osteoporosis secondary to SARS‐CoV‐2 infection. Key mechanisms include an imbalance between osteoclast and osteoblast activity driven by direct viral effects on bone, inflammation, hypoxia, dysregulation of noncoding RNAs, and metabolic
Jinlong Wang   +5 more
wiley   +1 more source

Epidemic trend analysis of SARS‐CoV‐2 in South Asian Association for Regional Cooperation countries using modified susceptible‐infected‐recovered predictive model

open access: yesEngineering Reports, Volume 5, Issue 1, January 2023., 2023
An short‐mid‐long term prediction model has been designed to understand the early dynamics of the COVID‐19 epidemic in the southeast Asian region. Based on the proposed prediction model we estimated the epidemic trend of COVID‐19 outbreak in SAARC countries for 20 days (short term), 90 days (mid‐term), and 180 days (long term), respectively.
Samrat Kumar Dey   +4 more
wiley   +1 more source

Coronavirus Update 11-13-20 [PDF]

open access: yes, 2020
Active Cases --Rollovers for Meal Plans --Updated Exit Guidance for College Students from the Department of ...
The Coronavirus Planning Team,
core   +1 more source

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