Results 231 to 240 of about 264,219 (265)

Photogenerated fluphenazine radical cations for antiviral functionalization of polypropylene masks

open access: yesPolymer International, EarlyView.
Fluphenazine impregnated into nonwoven polypropylene masks is photoexcited to a radical cation, which inactivates viruses on the polymer surface without causing damage to the masks. Abstract The incorporation of photoactive molecules into polymeric substrates offers a compelling route to introduce advanced functionality while preserving the host ...
Lilian Martins‐Nascimento   +4 more
wiley   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo   +5 more
wiley   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said   +10 more
wiley   +1 more source

Active Cycle of Breathing Technique Versus Oscillating Positive Expiratory Pressure Therapy Versus Exercise With Huffing During an Exacerbation of Bronchiectasis: A Randomised, Controlled Trial

open access: yesRespirology, EarlyView.
Walking with huffing and the active cycle of breathing technique produced similar improvements in sputum expectoration and quality‐of‐life during hospitalisation for individuals experiencing a bronchiectasis exacerbation, while oscillating positive‐expiratory‐pressure therapy produced minimal changes.
Jennifer Phillips   +5 more
wiley   +1 more source
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Coronavirus?

Pediatrics, 1984
In Reply.— In both of our papers,1,2 we referred to coronavirus-associated disease and termed the particles "coronavirus-like." In order to make our position even less equivocal, we stated in our first paper (pages 213-214)1: "At present, because of the lack of viral propagation in tissue culture, the virions found in the stools are only
SOLANGE ROUSSET   +3 more
openaire   +1 more source

Inside the Coronavirus

Scientific American, 2022
Mark, Fischetti   +3 more
openaire   +2 more sources

Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks

Cell, 2021
William M Schneider   +2 more
exaly  

Hematology and oncology clinical care during the coronavirus disease 2019 pandemic

Ca-A Cancer Journal for Clinicians, 2020
Manish A Shāh   +2 more
exaly  

Clinical Characteristics of Coronavirus Disease 2019 in China

New England Journal of Medicine, 2020
Wei-Jie Guan, Yu Hu, Chun-Quan Ou
exaly  

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