Results 81 to 90 of about 1,322,570 (292)
Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors
Advanced Science, EarlyView.This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su +15 more
wiley +1 more source
, 2003 BACKGROUND: Health authorities worldwide, especially in the Asia Pacific region, are seeking effective public-health interventions in the continuing epidemic of severe acute respiratory syndrome (SARS).
Abu-Raddad, Laith J +18 more
core +1 more source
Drivers of MERS-CoV transmission: what do we know? [PDF]
, 2016 This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Memish, Ziad A.
core +1 more source
A Modular Vaccine Platform Against SARS‐CoV‐2 Based on Self‐Assembled Protein Nanoparticles
Advanced Science, EarlyView.A modular BP26 nanoparticle vaccine platform incorporating the SpyTag/SpyCatcher system enables high‐density, repetitive antigen display with post‐expression flexibility. Conjugation of the SARS‐CoV‐2 RBD to BP26 nanoparticles elicits strong humoral immunity and confers protection against viral challenge in vivo.
Seojung Lee +6 more
wiley +1 more source
Assessing the Burden of Coronavirus Disease 2019 (COVID-19) Among Healthcare Workers in Mexico City: A Data-Driven Call to Action [PDF]
, 2020 Neftalí Eduardo Antonio-Villa +6 more
openalex +1 more source
, 2003 We present an analysis of the first 10 weeks of the severe acute respiratory syndrome (SARS) epidemic in Hong Kong. The epidemic to date has been characterized by two large clusters-initiated by two separate "super-spread" events (SSEs)-and by ongoing ...
Abu-Raddad, Laith J +19 more
core +1 more source
The Coronavirus: Biopolitics and the Rise of ‘Anthropocene Authoritarianism’ [PDF]
, 2020 If the lesson of the global response to the Coronavirus is that humanity itself is the problem, then Anthropocene Authoritarianism looks set to pose a larger long-term challenge to our ways of life than the virus itself.
Chandler, D., Chandler, D.
core
Advanced Science, EarlyView.A microfluidic electrochemical biosensor enables sensitive and specific detection of antibodies associated with vaccine‐induced immune thrombotic thrombocytopenia (VITT) and heparin‐induced thrombocytopenia (HIT). The platform uses two antigen targets— platelet factor 4 (PF4) and cross‐linked‐PF4 (c‐PF4)—and microliter volumes of patient sera to ...
Diana F. Cedillo‐Alcantar +8 more
wiley +1 more source
Love thy neighbour? Coronavirus politics and their impact on EU freedoms and rule of law in the Schengen Area. CEPS Paper in Liberty and Security in Europe No. 2020-04, April 2020 [PDF]
, 2020 Restrictions on international and intra-EU traffic of persons have been at the heart of the political responses to the coronavirus pandemic. Border controls and suspensions of entry and exist have been presented as key policy priorities to prevent the ...
Carrera, Sergio, Luk, Ngo Chun
core
Single‐Target Pairing System (StarPair) for Large‐Scale Interrogation of Cell–Cell Interactions
Advanced Science, EarlyView.This work presents a single‐target pairing system, StarPair, enabling cell–cell interaction studies by target combination in droplets. StarPair offers superior pairing efficiencies over 95% and operation frequencies of 105 pairs per 9.5 h for two‐target pairing, allowing large‐scale interrogation of immune cell‐cancer cell interactions and precise ...
Tianjiao Mao +6 more
wiley +1 more source