Results 81 to 90 of about 901,216 (306)

The riddle of the coronavirus

New Scientist, 2021
It is the many unknowns about covid-19 that make it so tricky to beat.
openaire   +2 more sources

Coronavirus HKU1 and Other Coronavirus Infections in Hong Kong [PDF]

Journal of Clinical Microbiology, 2006
ABSTRACT We have recently described the discovery of a novel coronavirus, coronavirus HKU1 (CoV-HKU1), associated with community-acquired pneumonia. However, the clinical spectrum of disease and the epidemiology of CoV-HKU1 infections in relation to infections with other respiratory viruses are unknown.
Lau, YL, So, LY, Tang, BSF, Yuen, KY, Yip, CCY, Woo, PCY, Lau, SKP, Lee, P, Lee, RA, Tse, H, Tsoi, HW, Cheng, VCC, Cheung, CHY, Chan, KH   +13 more
openaire   +4 more sources

Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
Engineering of the 148‐germline (148‐GL) antibody reveals a roadmap for overcoming SARS‐CoV‐2 viral escape. By introducing four specific somatic hypermutations, the resulting 148‐M4 variant restores potent neutralization against Omicron BA.1 and BA.4/5.
Huibin Lv, Ziqi Feng, Qi Wen Teo, Chunke Chen, Akshita B. Gopal, Danbi Choi, Timothy J. C. Tan, Yun Sang Tang, Lewis Siu, Armita Nourmohammad, Roberto Bruzzone, Ian A. Wilson, Meng Yuan, Nicholas C. Wu, Chris K. P. Mok   +14 more
wiley   +1 more source

Coronavirus disease 2019: reassembly attack of coronavirus

International Journal of Environmental Health Research, 2020
There have been three major global outbreaks of acute respiratory disease caused by coronavirus in the last two decades. The ongoing Coronavirus Disease 2019 (COVID-19) first emerged in Wuhan, China, is the most dangerous, which spread to 163 countries and 6 continents and caused a major public health emergency worldwide.
Yang, Chenglei, Qiu, Xue, Fan, Haoran, Jiang, Mei, Lao, Xiaojie, Zeng, Yukeng, Zhang, Zhiming   +6 more
openaire   +2 more sources

Canonical Antibodies Adopt Distinct Binding Modes to Recognize Viral Glycan Shields

Advanced Science, EarlyView.
Canonical Y‐shaped antibodies recognize viral glycan shields through adaptive Fab assembly states shaped by glycan organization and somatic hypermutation. Structural analyses ofbroadly neutralizing antibodies VRC35 and VRC36 across glycoproteins of HIV‐1, influenza, SARS‐CoV‐2, and Lassa viruses reveal distinct Fab assembly states, spanning monovalent,
Jiaxuan Cheng, Evan M. Cale, Amirabbas Maghsoudi, Matthew S. Sutton, Nancy S. Longo, Rebecca A. Gillespie, Lingshu Wang, Ivan Kosik, Sue Chong, Atsuhiro Yasuhara, Tatsiana Bylund, Arne Schön, Prabhanshu Tripathi, Yaroslav Tsybovsky, Haotian Lei, Nicholas C. Morano, Allison B. Lupatkin, Abraham J. Morton, Zabrina C. Lang, Jordan E. Becker, Isabella R. Frascilla, Myungjin Lee, Ning Li, Cuiping Liu, Ryan S. Roark, Chen‐Hsiang Shen, I‐Ting Teng, David J. Van Wazer, Danyi Wang, Lingyuan Wu, Goran Ahlsen, Mike Castro, Haijuan Du, Michael J. Ernandes, Tiansheng Li, Bob C. Lin, Mark K. Louder, Krisha McKee, Jonah S. Merriam, Sijy O'Dell, Li Ou, Sergei Pletnev, David Prikryl, Qi Qiu, Sarah Rubin, Mallika Sastry, Stephen D. Schmidt, Asif Shajahan, Andrea R. Shiakolas, Sanjay Srivatsan, Baoshan Zhang, Qiong Zhou, Mark Connors, Jason G. Gall, Yicheng Guo, Rick K. Huang, Yaoxing Huang, Richard A. Koup, Q. Paula Lei, John R. Mascola, Reda Rawi, Leonid Serebryannyy, Lawrence Shapiro, Zizhang Sheng, David D. Ho, Patrick C. Wilson, Jonathan W. Yewdell, Theodore C. Pierson, Masaru Kanekiyo, Nicole A. Doria‐Rose, Peter D. Kwong, Tongqing Zhou   +71 more
wiley   +1 more source

Association of infection-induced antibody levels with risk of subsequent SARS–COV-2 reinfection among healthcare professionals, Rhode Island, 1 March 2020–17 February 2021

Microbiology Spectrum
Numerous studies have investigated vaccine-induced correlates of protection (CoP) against severe acute respiratory syndrome–coronavirus 2 (SARS–CoV-2) infection, but data on infection-induced CoP are limited.
Jianrong Shi, M. Gayle Gabriel, Monica Epperson, Phil A. Chan, Jefferson M. Jones, Lyle R. Petersen, Melissa Briggs Hagen, Natalie J. Thornburg, Sharon Saydah, Claire M. Midgley   +9 more
doaj   +1 more source

Rapid Resolution of Non-Effusive Feline Infectious Peritonitis Uveitis with an Oral Adenosine Nucleoside Analogue and Feline Interferon Omega

Viruses, 2020
This is the first report of a successful treatment of a non-effusive feline infectious peritonitis (FIP) uveitis case using an oral adenosine nucleoside analogue drug and feline interferon omega, and alpha-1 acid glycoprotein (AGP) as an indicator of ...
Diane D. Addie, Johanna Covell-Ritchie, Oswald Jarrett, Mark Fosbery   +3 more
doaj   +1 more source

Perception of COVID-19 Vaccination Amongst Physicians in Colombia

Vaccines, 2021
Introduction: The SARS-CoV-2/COVID-19 pandemic has triggered the need to develop rapidly effective and safe vaccines to prevent infection, particularly in those at-risk populations such as medical personnel.
Jorge L. Alvarado-Socarras, Andrea Liliana Vesga-Varela, Doris Cristina Quintero-Lesmes, Marcela M. Fama-Pereira, Norma C. Serrano-Diaz, Mauricio Vasco, Virgil Carballo-Zarate, Lysien I. Zambrano, Alberto Paniz-Mondolfi, Alfonso J. Rodriguez-Morales   +9 more
doaj   +1 more source

Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants

Advanced Science, EarlyView.
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer, Rong Zhu, Manuel Reithofer, Gerhard Stadlmayr, Katharina Stadlbauer, Panchika Prangkio, Christoph Rippel, Markus Hahn, Aniko Eva Kasztner, Stefanie Stohl, Petr Bednar, Daniel Ruzek, David Glück, Robert Tampé, Gordana Wozniak‐Knopp, Yoo Jin Oh, Miriam Klausberger, Peter Hinterdorfer   +17 more
wiley   +1 more source

Seroprevalence of SARS-CoV-2 IgG antibodies in children seeking medical care in Seattle, WA June 2020 to December 2022

Microbiology Spectrum
Seroprevalence studies play an important role in estimating the number of children infected with SARS-CoV-2. We report SARS-CoV-2 seroprevalence in children seeking medical care for any reason at a free-standing pediatric hospital in Seattle, WA over a 2.
Amanda L. Adler, Alpana Waghmare, Kirsten Lacombe, Jane A. Dickerson, Alexander L. Greninger, Melissa Briggs Hagen, Kimberly Pringle, Tarayn Fairlie, Claire M. Midgely, Janet A. Englund   +9 more
doaj   +1 more source