Results 161 to 170 of about 5,490,593 (301)

Prolonged fenfluramine use in open‐label studies of Dravet or Lennox–Gastaut syndromes: Long‐term safety, tolerability, patient global functioning, and considerations for interpreting effectiveness

open access: yesEpilepsia, EarlyView.
This graphical abstract provides an overview of the content from this open‐label extension study of fenfluramine use in patients with Dravet syndrome or Lennox‐Gastaut syndrome. Abstract Objective Long‐term safety and global functioning are reported in patients with Dravet syndrome (DS) or Lennox–Gastaut syndrome (LGS) treated with fenfluramine in an ...
Antonio Gil‐Nagel   +18 more
wiley   +1 more source

Postoperative reduction of anti‐seizure medication is associated with cognitive improvement in seizure‐free patients after anterior temporal lobectomy

open access: yesEpilepsia, EarlyView.
Abstract Objective To determine whether postoperative reduction of anti‐seizure medication (ASM) burden is associated with cognitive improvement after anterior temporal lobectomy (ATL) in seizure‐free patients. Methods We retrospectively analyzed data for adult patients with drug‐resistant temporal lobe epilepsy who underwent unilateral ATL between ...
Kazushi Ukishiro   +7 more
wiley   +1 more source

A Phase I study of the pharmacokinetics (PK), bioavailability, dose proportionality, safety, and tolerability of topiramate injection compared to Oral topiramate in healthy adult participants

open access: yesEpilepsia, EarlyView.
Abstract This Phase I study evaluated the safety, tolerability, and pharmacokinetics of a 30‐min topiramate injection (intravenous [IV] TPM) infusion compared with oral topiramate (oral TPM) in healthy adult participants. In this randomized, open‐label, dose escalation, crossover study with 37 healthy participants received single doses of 50, 100, or ...
Adeboye O. Bamgboye   +3 more
wiley   +1 more source

The relationship between psychosocial job stressors and insomnia: The mediating role of psychological capital

open access: yesNursing Open, EarlyView., 2023
Abstract Aim This study aimed to examine the association of job‐related stressors and insomnia; to determine the association of psychological capital and insomnia; and to explore whether psychological capital mediates the association between job‐related stressors and insomnia among Chinese nurses. Design A cross‐sectional questionnaire survey.
Juan Du   +8 more
wiley   +1 more source

Coronavirus disease with multiple infarctions [PDF]

open access: yesQJM: An International Journal of Medicine, 2020
Imoto, W   +5 more
openaire   +2 more sources

Randomized Phase II Trial of Consolidation Pembrolizumab After Definitive Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma: KCSG HN19‐09, CONPELAN Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Background The benefit of consolidation programmed cell death protein 1 (PD‐1) blockade after chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma (NPC) remains unclear. Methods Patients with stages II–IVB NPC were randomized (2:1) to pembrolizumab 200 mg or placebo every 3 weeks for up to 17 cycles after chemoradiotherapy ...
Sang Hoon Chun   +11 more
wiley   +1 more source

Coronavirus disease 2019 (COVID-19) and miners with serious underlying medical conditions [Spanish]

open access: yes
Coronavirus disease 2019 (COVID-19) and miners with serious underlying medical conditions [Spanish]El COVID-19 es una enfermedad respiratoria que puede propagarse de persona a persona.cdc.gov/coronavirus-esCS 317330-D 06/11 ...

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