Results 141 to 150 of about 5,490,593 (301)

Platelets in Coronavirus Disease 2019 [PDF]

open access: yesSeminars in Thrombosis and Hemostasis, 2020
Larsen, Julie Brogaard   +2 more
openaire   +3 more sources

Blockchain Technology and the Circular Economy Transition: Associations With Company Performance

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT The adoption of circular economy (CE) practices in the private sector has received increasing academic and managerial attention, although the implementation of such practices continues to face significant barriers. Among Industry 4.0 technologies, blockchain has been identified as a potential factor associated with the CE transition.
Josep Llach   +3 more
wiley   +1 more source

Characterization and immunogenicity of nanoparticle vaccines displaying embecovirus spike proteins

open access: yesBiotechnology Progress, EarlyView.
Virus‐like particle vaccines displaying spike proteins from OC43, HKU1 A, and HKU1 B were evaluated in mice for their ability to elicit antibodies against the spike proteins from OC43, HKU1 A, HKU1 B, and HKU1 C. Abstract Endemic human coronaviruses OC43 and HKU1 cause widespread respiratory infections and can be associated with severe illness in ...
Peter J. Halfmann   +6 more
wiley   +1 more source

Deep impact of COVID-19 in the healthcare of Latin America: the case of Brazil

open access: yesBrazilian Journal of Infectious Diseases, 2020
Sergio Cimerman   +3 more
doaj   +1 more source

Quantification of Palmar and Digital Epidermal Thickness and Sweat Duct Density

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Palmar digital skin, with its high density of epidermal sweat glands and unique stratum corneum, derives its autonomic innervation from peripheral nerves. Understanding the changes to these structures could serve as objective proxy markers following peripheral nerve injury and interventions to promote regeneration.
Elizabeth Jones   +7 more
wiley   +1 more source

Coronavirus disease 2019 (COVID-19) and mining [Spanish]

open access: yes
Coronavirus disease 2019 (COVID-19) and mining [Spanish]El COVID-19 es una enfermedad respiratoria que puede propagarse de persona a persona.Los mineros y los operadores deben tomar medidas para prevenir enfermarse y propagar el COVID-19.cdc.gov ...

core  

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

open access: yesChemistry – A European Journal, EarlyView.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier   +7 more
wiley   +1 more source

Substrate‐Selective Inhibition of the SARS‐CoV‐2 Papain‐Like Protease: Inhibition of Hydrolysis of Human Over Viral Substrates

open access: yesChemistry – A European Journal, EarlyView.
The SARS‐CoV‐2 papain‐like protease (PLpro) is a medicinal chemistry target. Here we report mass spectrometry assays employing oligopeptide substrates based on the sequences of the viral polyproteins 1a/1ab and on an ISG15‐modified human protein, which enabled the identification of substrate‐selective PLpro inhibitors.
Sakshi Sharma   +13 more
wiley   +1 more source

External Control Arms in Japan: A Systematic Case Analysis of Documented Regulatory Implementation and Uncertainty Management

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1068-1080, October 2026.
External control arms (ECAs) have emerged as important tools to provide benchmark evidence on comparator effectiveness and thereby support regulatory decision making in situations where randomized controlled trials are difficult to conduct. However, how key methodological elements for ECAs are documented and implemented in practice and how residual ...
Suguru Okami, Alexandros Sagkriotis
wiley   +1 more source

Home - About - Disclaimer - Privacy