Results 251 to 260 of about 5,490,593 (301)

Cytokine-driven modulation of peripheral immune cell populations in Coronavirus disease 2019 patients. [PDF]

Front Immunol
Choto TA, Ndlovu B, Naicker T, Mduluza T.   +3 more
europepmc   +1 more source

Multimodal artificial intelligence in medical biotechnology: Integrating genomics, imaging, and clinical data for precision therapeutics

Precision Medical Sciences, EarlyView.
Overview of multimodal artificial intelligence (AI) for precision therapeutics. Diverse biomedical data modalities, including multi‐omics, medical imaging, digital pathology, electronic health records, wearable‐device data, and molecular information, are integrated through multimodal AI frameworks incorporating fusion strategies, foundation models ...
Gedion Mengistu Dejen
wiley   +1 more source

Examining the state of telehealth for mental health and substance use care after the coronavirus disease 2019 pandemic: An integrative review. [PDF]

J Int Med Res
Marie SE.
europepmc   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo, Woojin Jung, Tham Thi Bui, Hwi‐yeol Yun, Jung‐woo Chae, Jeremiah D. Momper   +5 more
wiley   +1 more source

Evaluation of artificial intelligence identified ipratropium bromide for the treatment of coronavirus disease 2019. [PDF]

Sci Rep
Jung DS, Cheon S, Kim CM, Seo JW, Sung SJ, Kim DY, Lee JH, Kim W, Kang J, Yun NR, Kim YR, Kim DM.   +11 more
europepmc   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said, Job R. Schippers, Leila Atmowihardjo, Yingxue Li, Mick S. van der Plas, Harm J. Bogaard, Lieuwe D. J. Bos, Ron A. A. Mathôt, Jurjan Aman, Eleonora L. Swart, Imke H. Bartelink   +10 more
wiley   +1 more source

Ascertaining the Kawasaki Disease-Coronavirus Disease 2019 Linkage in a Japanese Administrative Claims Database. [PDF]

Pediatr Int
Mizuno T, Suzuki J, Takahashi S, Imai H, Itagaki H, Akaba T, Yoshida M, Endo S.   +7 more
europepmc   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

Phytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko, Victoriya Georgiyants, Liudas Ivanauskas, Olha Mykhailenko   +3 more
wiley   +1 more source

Role of defensins in immunothrombosis

Rheumatology &Autoimmunity, EarlyView.
Defensins are important proteins that link the immune system and blood clotting, playing a key role in immunothrombosis. α‐defensins mainly come from neutrophils, while β‐defensins are produced by epithelial cells and platelets. These proteins help form blood clots in several ways: they slow down clot breakdown (fibrinolysis), activate platelets, and ...
Yuebing Wang, Guijuan Guo, Xiangjun Liu, Xiaoyu Chen, Wenqiong Wang, Patapong Towiwat, Ru Li, Chun Li   +7 more
wiley   +1 more source

Preemptive rapid antigen test as an emergency measure during coronavirus disease 2019 outbreaks. [PDF]

Front Public Health
Pan Y, Liu Y, Jiang Y, Cai J.
europepmc   +1 more source