Results 261 to 270 of about 10,287,555 (319)

The predictive value of the National Early Warning Score for mortality and independent prognostic factors in patients with coronavirus disease 2019: A retrospective cohort study. [PDF]

J Int Med Res
Zhang X, Li F.
europepmc   +1 more source

Disease Burden of Liver Cancer and Its Underlying Etiologies Globally and in China From 1990 to 2021: Results From the Global Burden of Disease Study 2021

Portal Hypertension &Cirrhosis, EarlyView.
Liver cancer remains a leading global health threat, imposing a substantial and growing burden of disease and disability. This study explores the epidemiologic landscape of liver cancer worldwide and within China over recent decade using Global Burden of Disease database 2021 study.
Jiaqi Ruan, Hangkai Huang, Chengfu Xu
wiley   +1 more source

The Change in Healthcare-Associated Infections in Intensive Care Units Associated with the Coronavirus Disease 2019 in Taiwan. [PDF]

Medicina (Kaunas)
Wang CY, Chen YH, Hsiao CC, Cheng CG, Cheng CA.   +4 more
europepmc   +1 more source

Novel applications of the tomato microbiome: Roles and considerations for agriculture, human health, and society

PLANTS, PEOPLE, PLANET, EarlyView.
Plants, like humans, have a microbiome that helps them grow, defend themselves against pathogens, acquire nutrients, and protect themselves against environmental stresses. The microbiome of tomatoes, a staple crop grown worldwide, could be utilized not only to reduce fertilizer and pesticide applications, but also to clean up harmful pollutants ...
Sean Lindert, Kathryn Kingsley, Peerapol Chiaranunt, James F. White   +3 more
wiley   +1 more source

Association between eosinophil counts and outcomes of severe coronavirus disease 2019 in elderly asthma patients: a prospective cohort study. [PDF]

J Thorac Dis
Avdeev SN, Gaynitdinova VV, Chikina SY, Merzhoeva ZM, Nuralieva GS, Gneusheva TY, Sokolova ES, Bogatyreva TU, Berikkhanov ZG, Ma Q.   +9 more
europepmc   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo, Woojin Jung, Tham Thi Bui, Hwi‐yeol Yun, Jung‐woo Chae, Jeremiah D. Momper   +5 more
wiley   +1 more source

Exploratory characterization of dynamic soluble programmed death-ligand 1 trajectories and their association with mortality in critical coronavirus disease 2019. [PDF]

J Intensive Care
Takeuchi S, Kawamoto E, Matsusaki T, Ono D, Sakakura Y, Gaowa A, Park EJ, Shimaoka M, Kaku R.   +8 more
europepmc   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said, Job R. Schippers, Leila Atmowihardjo, Yingxue Li, Mick S. van der Plas, Harm J. Bogaard, Lieuwe D. J. Bos, Ron A. A. Mathôt, Jurjan Aman, Eleonora L. Swart, Imke H. Bartelink   +10 more
wiley   +1 more source

Coronavirus disease 2019-associated liver injury in pregnancy: A case report. [PDF]

J Int Med Res
Yu N, Huang YY, Feng L, Liu Q.
europepmc   +1 more source

Deep Learning–Driven Surface‐Enhanced Raman Scattering–Lateral Flow Immunoassay With Au Nanostars for High‐Accuracy Respiratory Virus Detection

Rare Metals, EarlyView.
ABSTRACT The high accuracy in surface‐enhanced Raman scattering‐lateral flow immunoassays (SERS–LFIAs) is critical for reliable point‐of‐care testing (POCT) in clinical diagnostics. Conventional approaches are often affected by sampling variability and uneven distribution of immunoprobes, leading to unreliable signal fluctuations.
Shuai Zhao, Yan‐Yan Li, Cheng‐Long Lin, Mei‐Mei Xu, Wei‐Da Zhang, Dan Li, Yu‐Si Peng, Masaki Tanemura, Tian‐Shuo Zhao, Yong Yang   +9 more
wiley   +1 more source