Results 61 to 70 of about 5,490,593 (301)

Seroprevalence of IgG antibodies to SARS-coronavirus in asymptomatic or subclinical population groups. [PDF]

, 2006
We systematically reviewed the current understanding of human population immunity against SARS-CoV in different groups, settings and geography. Our meta-analysis, which included all identified studies except those on wild animal handlers, yielded an ...
Donnelly, CA, Hedley, AJ, Ferguson, NM, Ho, LM, Lam, T-H, Ghani, AC, Anderson, RM, Lam, TH, Ho, L-M, Riley, S, Leung, GM, Fraser, C, Lim, WW   +12 more
core   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Optimizing surveillance post-pandemic: an evaluation of COVID-19 and other respiratory virus surveillance systems in the Philippines, April 2023

BMC Public Health
Background On May 5, 2023, the World Health Organization removed the public health emergency of international concern (PHEIC) designation for the COVID-19 pandemic, noting reduced global risk of severe COVID-19 due to widespread infection and vaccine ...
Hannah Lofgren, Morgane Donadel, Romel S. Lacson, Devon Ray Pacial, Alethea R. de Guzman, Olivia Almendares, Philippines COVID-19 Surveillance System Evaluation Team   +6 more
doaj   +1 more source

Detection and Profiling of Human Coronavirus Immunoglobulins in Critically Ill Coronavirus Disease 2019 Patients

Critical Care Explorations, 2021
Objectives:. Coronavirus disease 2019 continues to spread worldwide with high levels of morbidity and mortality. We performed anticoronavirus immunoglobulin G profiling of critically ill coronavirus disease 2019 patients to better define their underlying
Douglas D. Fraser, MD, PhD, Gediminas Cepinskas, DVM, PhD, Marat Slessarev, MD, MSc, Claudio M. Martin, MD, MSc, Mark Daley, PhD, Maitray A. Patel, BSc, Michael R. Miller, PhD, Eric K. Patterson, PhD, David B. O’Gorman, PhD, Sean E. Gill, PhD, Susanne Oehler, PhD, Markus Miholits, MSc, Brian Webb, PhD, on behalf of the Lawson COVID-19 Study Team, Robert Arntfield, Ian Ball, Gordon Barkwell, Tracey Bentall, Karen Bosma, Saoirse Cameron, Eileen Campbell, David Carter, Carolina Gillio-Meina, Robert Hegele, Natalya Odoardi, Ram Singh, Kelly Summers, Sue Tereschyn   +27 more
doaj   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source

Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences

Advanced Science, EarlyView.
This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu, Pan Zhang, Shangqian Wu, Hao Sun, Minwei Li, Sophia Tsoka, Zizhang Sheng, Lei Deng   +7 more
wiley   +1 more source

Knowledge, attitude, and practice of coronavirus disease 2019 disease among patients attending coronavirus disease 2019-screening OPD

Egyptian Journal of Chest Disease and Tuberculosis, 2022
Importance This study was conducted in the early and middle stages of coronavirus disease 2019 (COVID-19) pandemic in India. It helps in gaining knowledge about the virus and taking steps to prevent the pandemic.
Kotyal Umamaheshwarappa Vivek, Bangalore Lakshmanamurthy Shashibhushan, Channarayanahalli Lakshmanna Nagaraja   +2 more
doaj   +1 more source

Comparative evaluation of SARS-CoV-2 laboratory testing data sources for U.S. COVID-19 public health surveillance, 2020–2024

Frontiers in Public Health
IntroductionSARS-CoV-2 laboratory testing data were collected by the U.S. Centers for Disease Control and Prevention for surveillance during the COVID-19 pandemic response.
Alisha Kalangara, Alisha Kalangara, Conor Millard, Conor Millard, Amber K. Winn, Tricia A. Aden, Kim Del Guercio, Kim Del Guercio, Jourdan DeVies, Stephanie Dietz, Andrew Godoshian, Jason Hall, Jason Hall, Teresa Jue, Joseph Miller, Erica Billig Rose, Zachary R. Smith, Benjamin J. Silk   +17 more
doaj   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source