Results 111 to 120 of about 468,607 (303)

Investigating ethnic inequalities in the incidence of sexually transmitted infections: mathematical modelling study.

, 2004
OBJECTIVES: To investigate ethnic differences in rates of gonorrhoea using empirical sexual behaviour data in a simple mathematical model. To explore the impact of different intervention strategies in this simulated population. METHODS: The findings from
Ghani, AC, Low, N, Garnett, GP, Sterne, JAC, Turner, K M E, Turner, KME   +5 more
core   +1 more source

New coronavirus infection (COVID-19) and kidney-urinary tract diseases / pathological conditions

, 2022
The main target of the new coronavirus infection (COVID19), spread by the SARS-CoV-2 virus, is the respiratory system. SARS-CoV-2 infection can cause kidney damage, and severe renal dysfunction is more common in patients with chronic comorbid/multimorbid
D.I. Trukhan
core   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

Distinct characteristics on mixed infection of SARS-CoV-2 variants and other respiratory pathogens among patients with acute COVID-19 in central China

Frontiers in Cellular and Infection Microbiology
BackgroundReports on mixed infection with different severe acute respiratory syndrome coronavirus 2 variants and other respiratory pathogens in patients with acute coronavirus disease in China remain scarce.
Yiman Geng, Youhua Yuan, Xuhong Lin, Jingjing Wei, Qi Zhang, Xiaohuan Mao, Xiaohuan Zhang, Xiulei Zhang, Yuan Zhang, Jing Zhao, Fengxia Guo, Peiming Zheng   +11 more
doaj   +1 more source

Essential work, invisible workers: The role of digital curation in COVID‐19 Open Science

Journal of the Association for Information Science and Technology, Volume 76, Issue 4, Page 703-717, April 2025.
Abstract In this paper, we examine the role digital curation practices and practitioners played in facilitating open science (OS) initiatives amid the COVID‐19 pandemic. In Summer 2023, we conducted a content analysis of available information regarding 50 OS initiatives that emerged—or substantially shifted their focus—between 2020 and 2022 to address ...
Irene V. Pasquetto, Amina A. Abdu, Natascha Chtena   +2 more
wiley   +1 more source

Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong.

, 2003
BACKGROUND: Health authorities worldwide, especially in the Asia Pacific region, are seeking effective public-health interventions in the continuing epidemic of severe acute respiratory syndrome (SARS).
Kong, James HB, Leung, Gabriel M, Lau, Edith MC, Ghani, Azra C, Ho, Lai-Ming, Anderson, Roy M, Chan, King-Pan, Riley, Steven, Hedley, Anthony J, Tse, Lai-Yin, Liu, Shao-Haei, Donnelly, Christl A, Chau, Patsy, Abu-Raddad, Laith J, Tsang, Thomas, Lam, Tai-Hing, Ferguson, Neil M, Fraser, Christophe, Thach, Thuan-Quoc   +18 more
core   +1 more source

Inflammation‐driven variability in drug metabolism: Insights from voriconazole treatment of HSCT recipients

British Journal of Clinical Pharmacology, EarlyView.
Aims Voriconazole is commonly used to prevent fungal infections after haematopoietic stem cell transplantation (HSCT). Although its metabolism is influenced by CYP2C19 genetics and inflammation, their combined effect is rarely considered in clinical practice, and integrated analyses remain limited.
Sylvia D. Klomp, Martijn L. Manson, Henk‐Jan Guchelaar, Stefan Böhringer, Esther H. M. van Egmond, Peter A. von dem Borne, Jesse J. Swen   +6 more
wiley   +1 more source

Transmission dynamics of the etiological agent of SARS in Hong Kong: impact of public health interventions.

, 2003
We present an analysis of the first 10 weeks of the severe acute respiratory syndrome (SARS) epidemic in Hong Kong. The epidemic to date has been characterized by two large clusters-initiated by two separate "super-spread" events (SSEs)-and by ongoing ...
Lee, Koon-Hung, Leung, Gabriel M, Leung, Pak-Yin, Lau, Edith MC, Ghani, Azra C, Ho, Lai-Ming, Anderson, Roy M, Chan, King-Pan, Riley, Steven, Ho, William, Lo, Su-Vui, Hedley, Anthony J, Donnelly, Christl A, Chau, Patsy, Abu-Raddad, Laith J, Tsang, Thomas, Thach, Thuan Q, Lam, Tai-Hing, Ferguson, Neil M, Fraser, Christophe   +19 more
core   +1 more source

Population pharmacokinetic/pharmacodynamic modelling to evaluate favipiravir in combination with lopinavir–ritonavir in patients with COVID‐19

British Journal of Clinical Pharmacology, EarlyView.
Aims The repurposed use of favipiravir in COVID‐19 has been reported to have limited clinical efficacy, yet it has been widely used in some countries. Favipiravir causes mutagenesis in RNA viruses, and it is currently unknown whether it may have a measurable effect on the virus in humans.
Akosua A. Agyeman, Laura Buggiotti, Li‐An K. Brown, Jose A. Guerra‐Assuncao, Japhette E. Kembou‐Ringert, Wen Y. Mak, Judith Breuer, David M. Lowe, Joseph F. Standing, FLARE Investigators   +9 more
wiley   +1 more source

Neurotropic Coronavirus Infections [PDF]

, 2016
Neurotropic strains of the mouse hepatitis virus (MHV) cause a range of diseases in infected mice ranging from mild encephalitis with clearance of the virus followed by demyelination to rapidly fatal encephalitis. This chapter discusses the structure, life cycle, transmission, and pathology of neurotropic coronaviruses, as well as the immune response ...
Perlman, Stanley, Wheeler, D. Lori
openaire   +1 more source