Results 91 to 100 of about 468,607 (303)

Occupational health risk among healthcare workers during COVID-19 pandemic: actions to limit the risk

Journal of the Egyptian Public Health Association, 2021
The World Health Organization declared coronavirus infection 2019 (COVID-19) as a pandemic in March 2020. The infection with coronavirus started in Wuhan city, China, in December 2019. As of October 2020, the disease was reported in 235 countries.
Eman Casper
doaj   +1 more source

Mortality and progression to AIDS after starting highly active antiretroviral therapy.

, 2003
OBJECTIVES: To examine survival and progression to AIDS among HIV-infected patients after starting highly active antiretroviral therapy (HAART). METHODS: The study population consisted of 3724 patients from the ATHENA observational cohort who initiated ...
de Wolf, Frank, Lange, JMA, van Sighem, A.I., Ghani, Azra C, Reiss, Peter, Lange, J.M.A., Lange, Joep MA, van de Wiel, Mark A, Sighem, van, A.I., Wolf, de, F., Gyssens, ICJ (Inge), Ghani, A.C., Ghani, AC, Gyssens, I.C., de Lange, J., van Sighem, Ard I, Gyssens, Inge C, Jambroes, M, Jambroes, M., Wiel, MA Mark van de, Wolf, F de, de Wolf, F, Brinkman, K., Wiel, van de, M.A., Sighem, AI van, Reiss, P, Sighem, AI, Brinkman, K, ATHENA Cohort Study Group, Jambroes, Mariëlle, Brinkman, Kees, de Wolf, F., Gyssens, IC, van de Wiel, M.A., van de Wiel, MA, Reiss, P.   +35 more
core   +1 more source

RNA‐Binding Protein RBM25 Targets the mRNA Stability of GTPase Rab22a to Restrict Viral Entry and Infection

Advanced Science, EarlyView.
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding, Huiying Chen, Yuyu Jiang, Chunyan Zhao, Jie Bai, Yan Xiang, Zeting Wang, Xixi Wang, Bing Rui, Wanda Tang, Yue Ding, Zhenzhen Zhan, Yunkai Zhang, Xingguang Liu   +13 more
wiley   +1 more source

Challenges and Lessons from Novel Coronavirus Infection

Central Asian Journal of Medical Sciences, 2020
No absract  in ...
Gansukh Choijilsuren, Ariunzaya Bat-Erdene, Enkhsaikhan Lkhagvasuren   +2 more
doaj   +1 more source

Olfactory Bulb Volume Reflects Olfactory Dysfunction and Network Organization: Insights From the Population‐Based Rhineland Study

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Olfactory dysfunction is common in aging and an early symptom of neurodegenerative diseases, but how structural (olfactory bulb [OB] volume) and functional (olfactory network [OFN] functional connectivity [FC]) brain features interact to shape odor identification ability remains unclear.
Weiyi Zeng, Konstantinos Melas, Santiago Estrada, N. Ahmad Aziz, Monique M. B. Breteler   +4 more
wiley   +1 more source

An analysis of central venous catheter-related bloodstream infections in patients treated in a Swedish Covid-19 intensive care unit

SAGE Open Medicine
Background: Catheter-related bloodstream infection is a well-known, severe complication of central venous catheter insertion. Studies that have evaluated the coronavirus disease 2019 pandemic’s influence on the incidence of catheter-related bloodstream ...
Petter Lunnemar, Knut Taxbro, Fredrik Hammarskjöld   +2 more
doaj   +1 more source

vCJD risk in the Republic of Ireland. [PDF]

, 2003
BACKGROUND: The Republic of Ireland has the second highest incidence of BSE worldwide. Only a single case of vCJD has been identified to date. METHODS: We estimate the total future number of clinical cases of vCJD using an established mathematical model,
Howley, Rachel, Farrell, Michael, Harney, MS, CA Donnelly, Ghani, Azra C, Walsh, RM, Walsh, Rory McConn, Michael S Harney, Azra C Ghani, Rachel Howley, Brett, Francesca, Ghani Azra C, Ghani, AC, Howley, R, Howley Rachel, Farrell Michael, Walsh, Michael, Donnelly, CA, Francesca Brett, Farrell, M, Harney Michael S, Walsh Michael, Rory McConn Walsh, Brett Francesca, Walsh, M, Donnelly CA, Harney, Michael S, Michael Farrell, Brett, F, Michael Walsh, Walsh Rory   +30 more
core   +1 more source

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Factors determining the pattern of the variant Creutzfeldt-Jakob disease (vCJD) epidemic in the UK.

, 2003
Following the emergence of a new variant of Creutzfeldt-Jakob disease (vCJD) 6 years ago, and the gradual rise in clinical cases, there has been increased speculation regarding the overall magnitude of this epidemic in Great Britain.
Ghani, Azra C, Donnelly, Christl A, Anderson, Roy M, Ferguson, Neil M   +3 more
core   +1 more source

IRF‐1 modulates hepatic ferroptosis and aggravates liver ischemia/reperfusion injury via DYRK1α

Animal Models and Experimental Medicine, EarlyView.
IRF‐1 modulates hepatic ferroptosis and aggravates liver ischemia/reperfusion injury via DYRK1α. Abstract Background The purpose is to define the contribution of the interferon regulatory factor‐1–dual‐specificity tyrosine phosphorylation‐regulated kinase 1α (IRF‐1–DYRK1α) axis to hepatocellular ferroptosis during liver ischemia/reperfusion injury ...
Jinping Zhang, Jinming Zhang, Siyuan Song, Mingyang Li, Liying Sun, Zhijun Zhu, Dongdong Lin   +6 more
wiley   +1 more source