The new poor law and the health of the population of England and Wales
Abstract We estimate the impact of reductions in poor law expenditure on rural life expectancy and mortality rates in England and Wales following the 1834 Poor Law Amendment Act. Given the scale of cuts imposed, our estimates imply 8–10 per cent increases in mortality at ages 1–4 years and 2–4 per cent falls in rural expectation of life at birth.
David Green +3 more
wiley +1 more source
Aging Compromises Terminal Differentiation Program of Cytotoxic Effector Lineage and Promotes Exhaustion in CD8<sup>+</sup> T Cells Responding to Coronavirus Infection. [PDF]
Zhu Z +8 more
europepmc +1 more source
ABSTRACT Introduction Allogeneic hematopoietic stem cell transplantation (HSCT) offers curative potential for many hematological malignancies; however, outcomes may be adversely affected by infections and transplant‐associated complications, contributing to non‐relapse mortality (NRM).
Lara Bischof +17 more
wiley +1 more source
Integrative transcriptomic and proteomic analyses reveal that carbon metabolism and complement system of Madin Darby Bovine Kidney cells are affected by bovine coronavirus infection. [PDF]
Zhang H +9 more
europepmc +1 more source
Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Janine Fichtner +13 more
wiley +1 more source
The functional state of athletes who have undergone coronavirus infection (COVID-19). [PDF]
Zaborova V +8 more
europepmc +1 more source
Low serum transferrin predicts adverse outcome in COVID‐19 and is related to coagulation activity
British Journal of Haematology, EarlyView.
Lukas Lanser +4 more
wiley +1 more source
Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto +9 more
wiley +1 more source
Colorimetric Reverse Transcription Loop-Mediated Isothermal Amplification with Xylenol Orange Targeting Nucleocapsid Gene for Detection of Feline Coronavirus Infection. [PDF]
Khumtong K +11 more
europepmc +1 more source

