Results 81 to 90 of about 3,857,996 (335)

IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes.

Journal of Clinical Investigation, 2019
Type 1 IFNs (IFN-I) generally protect mammalian hosts from virus infections, but in some cases, IFN-I is pathogenic. Because IFN-I is protective, it is commonly used to treat virus infections for which no specific approved drug or vaccine is available ...
Rudragouda Channappanavar, Anthony R. Fehr, Jian Zheng, C. Wohlford-Lenane, J. Abrahante, M. Mack, R. Sompallae, P. McCray, D. Meyerholz, S. Perlman   +9 more
semanticscholar   +1 more source

Chinese expert consensus on the perinatal and neonatal management for the prevention and control of the 2019 novel coronavirus infection (First edition).

Annals of Translational Medicine, 2020
Since December 2019, there has been an outbreak of novel coronavirus (2019-nCoV) infection in China. Two cases of neonates with positive 2019-nCoV tests have been reported.
Laishuan Wang, Yuan Shi, T. Xiao, Jianhua Fu, Xing Feng, D. Mu, Qi Feng, M. Hei, Xiaojing Hu, Zhankui Li, G. Lu, Zezhong Tang, Yajuan Wang, Chuanqing Wang, S. Xia, Jianqing Xu, Yujia Yang, Jie Yang, M. Zeng, Jun Zheng, Wei Zhou, Xiaoyu Zhou, Xiaoguang Zhou, L. Du, Shoo K. Lee, Wenhao Zhou   +25 more
semanticscholar   +1 more source

COVID‐19 Vaccination is not Associated with the Development of Idiopathic Inflammatory Myositis in U.S. Veterans

Arthritis Care &Research, Accepted Article.
Objective Several case reports have proposed a potential association between COVID‐19 vaccination and the subsequent development of idiopathic inflammatory myositis (IIM). This study examined prior COVID‐19 vaccination in US Veterans who developed new‐onset IIM compared to those without new‐onset IIM.
Caleb Hernández, Naomi Schlesinger, Jorge Rojas, Jessica A. Walsh, Tawnie J Braaten, Gary A Kunkel, Makoto Jones, Brian C Sauer, Julio Facelli, Grant W. Cannon, Dorota Lebiedz‐Odrobina   +10 more
wiley   +1 more source

Endocrine and metabolic link to coronavirus infection

Nature Reviews Endocrinology, 2020
Type 2 diabetes mellitus and hypertension are the most common comorbidities in patients with coronavirus infections. Emerging evidence demonstrates an important direct metabolic and endocrine mechanistic link to the viral disease process. Clinicians need
S. Bornstein, R. Dalan, D. Hopkins, G. Mingrone, B. Boehm   +4 more
semanticscholar   +1 more source

Human Coronavirus Infections [PDF]

, 1995
The first report of a human coronavirus was in 1965 when Tyrrell and Bynoe (1965) isolated a virus from the nasal washings of a male child. The child had typical symptoms and signs of a common cold and the washing was found to be able to induce common colds in volunteers challenged intranasally.
openaire   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

Cerebral venous thrombosis in a patient with Down syndrome and coronavirus disease 2019: a case report

Journal of Medical Case Reports, 2021
Background The new coronavirus disease 2019 pandemic has spread throughout most of the world. Cerebral venous thrombosis is a rare thromboembolic disease that can present as an extrapulmonary complication in coronavirus disease 2019 infection.
Henry Robayo-Amortegui, Natalia Valenzuela-Faccini, Cesar Quecano-Rosas, Darlyng Zabala-Muñoz, Michel Perez-Garzon   +4 more
doaj   +1 more source

How Drivers of Seasonality in Respiratory Infections May Impact Vaccine Strategy: A Case Study in How Coronavirus Disease 2019 (COVID-19) May Help Us Solve One of Influenza’s Biggest Challenges [PDF]

, 2022
Eric Lofgren, Elena N. Naumova, Jack Gorski, Yuri N. Naumov, Nina H. Fefferman   +4 more
openalex   +1 more source

Inactivating SARS‐CoV‐2 Virus with MOF‐Composites as Smart Face Masks

Advanced Functional Materials, EarlyView.
In situ preparation and functionalization of MOF@Cotton fabrics as smart face masks for the immobilization of proteins and inactivation viruses, such as SARS‐CoV‐2. Abstract The significant impact of the SARS‐CoV‐2 (COVID‐19) pandemic outbreak on people's lives has highlighted the urgent need for effective personal protective equipment.
Romy Ettlinger, Aamod V. Desai, Hau Lam Jody Cheong, Louise L. Major, Terry K. Smith, Aaron B. Naden, Jane Hilton, Catherine S. Adamson, A. Robert Armstrong, Russell E. Morris   +9 more
wiley   +1 more source

Clinical course and outcome of 107 patients infected with the novel coronavirus, SARS-CoV-2, discharged from two hospitals in Wuhan, China

Critical Care, 2020
Background In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of COVID-19 was not thoroughly described.
Dawei Wang, Yimei Yin, Chang Hu, Xing Liu, Xingguo Zhang, Shuliang Zhou, Mingzhi Jian, Haibo Xu, John Prowle, Bo Hu, Yirong Li, Zhiyong Peng   +11 more
doaj   +1 more source