Results 91 to 100 of about 402,323 (301)

DMS‐MaPseq and DREEM Analyses Implicate the Critical Role of RNA Structural Dynamics in Turnip Yellow Mosaic Virus Pathogenicity

Advanced Science, EarlyView.
RNA structural profiling of Turnip Yellow Mosaic Virus by DMS‐MaPseq and DREEM analyses uncover that viral genome‐wide RSS is highly complicated and heterogeneous, with alternative RSSs widely distributed across the genome. Notably, the viral 3’ tRNA‐like structure adopts alternative conformations in vivo.
Jiaying Zhu, Changhao Li, Chisimbily Onyia, Xindi Li, Xingxing Yan, Songxiao Zhong, Taerin Oh, Xiuren Zhang   +7 more
wiley   +1 more source

RNA‐Binding Protein RBM25 Targets the mRNA Stability of GTPase Rab22a to Restrict Viral Entry and Infection

Advanced Science, EarlyView.
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding, Huiying Chen, Yuyu Jiang, Chunyan Zhao, Jie Bai, Yan Xiang, Zeting Wang, Xixi Wang, Bing Rui, Wanda Tang, Yue Ding, Zhenzhen Zhan, Yunkai Zhang, Xingguang Liu   +13 more
wiley   +1 more source

Prevalence of lymphoreticular prion protein accumulation in UK tissue samples. [PDF]

, 2004
This study aims to provide an estimate of the number of individuals in the UK who may be incubating variant Creutzfeldt-Jakob disease and at risk of causing iatrogenic spread of the disease.
Ironside, James W, McCardle, Linda, Ritchie, Diane, Edwards, Philip, Penney, Mark, Conyers, Lisa, Ghani, Azra C, Hilton, David A, Hegazy, Doha   +8 more
core   +1 more source

ESPORTS IN TIMES OF A GLOBAL PANDEMIC: OPPORTUNITIES AND FUTURE CHALLENGES WHEN TRANSFORMING GAMING INTO A SPORT IN COSTA RICA

Pensar en Movimiento, 2020
Rojas-Valverde, D., Fallas-Campos, A. & Alpízar-Alpízar, M. (2020). Esports in times of a global pandemic: opportunities and future challenges when transforming gaming into a sport in Costa Rica.
Daniel Rojas-Valverde, Andrea Fallas-Campos, Mildred Alpízar-Alpízar   +2 more
doaj   +1 more source

Arterial Blood‐Mediated Deep‐Tissue Photoacoustic Oximetry

Advanced Science, EarlyView.
The arterial prior method (APM+) for photoacoustic oximetry is introduced, which leverages the high arterial blood oxygenation to calibrate the fluence at the artery and estimate the oxygenation of the surrounding tissue, thus circumventing the spectral coloring problem. APM+’s accuracy and consistency are shown in a series of phantom and in vivo human
Karteekeya Sastry, Junhao Zhu, Joshua Olick‐Gibson, Li Lin, Lei Li, Jigmi Basumatary, Yang Zhang, Lihong V. Wang   +7 more
wiley   +1 more source

Guidance for preventive and responsive measures to coronavirus for jails, prisons, immigration detention and youth facilities [PDF]

, 2020
The coronavirus, or COVID-19, has been declared by the World Health Organization to be a global pandemic. As the number of people infected in the United States grows exponentially, we must focus on prevention and containment in the criminal and ...
Vera Institute of Justice
core  

COVID-19 pandemic impacts to Dentistry

RGO: Revista Gaúcha de Odontologia, 2020
Objective: To achieve a literature review on the impacts of COVID-19 on dentistry. Methods: Analysis of scientific articles contained in the LILACS and PubMed platforms that fulfill the informative purpose of the research.
Matheus Simões MEDEIROS, Haniel Laurentino Ferreira dos SANTOS, Jaqueline Oliveira BARRETO, Julliana Cariry Palhano FREIRE, Eduardo DIAS-RIBEIRO   +4 more
doaj   +1 more source

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

Distinct characteristics on mixed infection of SARS-CoV-2 variants and other respiratory pathogens among patients with acute COVID-19 in central China

Frontiers in Cellular and Infection Microbiology
BackgroundReports on mixed infection with different severe acute respiratory syndrome coronavirus 2 variants and other respiratory pathogens in patients with acute coronavirus disease in China remain scarce.
Yiman Geng, Youhua Yuan, Xuhong Lin, Jingjing Wei, Qi Zhang, Xiaohuan Mao, Xiaohuan Zhang, Xiulei Zhang, Yuan Zhang, Jing Zhao, Fengxia Guo, Peiming Zheng   +11 more
doaj   +1 more source

Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
Engineering of the 148‐germline (148‐GL) antibody reveals a roadmap for overcoming SARS‐CoV‐2 viral escape. By introducing four specific somatic hypermutations, the resulting 148‐M4 variant restores potent neutralization against Omicron BA.1 and BA.4/5.
Huibin Lv, Ziqi Feng, Qi Wen Teo, Chunke Chen, Akshita B. Gopal, Danbi Choi, Timothy J. C. Tan, Yun Sang Tang, Lewis Siu, Armita Nourmohammad, Roberto Bruzzone, Ian A. Wilson, Meng Yuan, Nicholas C. Wu, Chris K. P. Mok   +14 more
wiley   +1 more source