Results 81 to 90 of about 402,323 (301)

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong. [PDF]

, 2003
BACKGROUND: Health authorities worldwide, especially in the Asia Pacific region, are seeking effective public-health interventions in the continuing epidemic of severe acute respiratory syndrome (SARS).
Kong, James HB, Leung, Gabriel M, Lau, Edith MC, Ghani, Azra C, Ho, Lai-Ming, Anderson, Roy M, Chan, King-Pan, Riley, Steven, Hedley, Anthony J, Tse, Lai-Yin, Liu, Shao-Haei, Donnelly, Christl A, Chau, Patsy, Abu-Raddad, Laith J, Tsang, Thomas, Lam, Tai-Hing, Ferguson, Neil M, Fraser, Christophe, Thach, Thuan-Quoc   +18 more
core   +1 more source

Equine Coronavirus Infection [PDF]

, 2017
Equine coronavirus (ECoV) is an emerging virus associated clinically and epidemiologically with fever, depression, anorexia, and less frequently colic or diarrhea in adult horses. Sporadic cases and outbreaks have been reported with increased frequency since 2010 from Japan, the USA, and more recently from Europe.
Pusterla, Nicola, Vin, Ron, Leutenegger, Christian, Mittel, Linda D., Divers, Thomas J.   +4 more
openaire   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Farm animal coronaviruses: the solution is in vaccines

Veterinary Quarterly
RNA-containing coronaviruses are widespread in nature and can infect a number of vertebrates. Animals are potential sources of human coronaviruses diseases, and interspecies infection by animal coronaviruses has been recorded several times.
Olga Kondakova, Anna Tsybina, Ekaterina Evtushenko, Ekaterina Ryabchevskaya, Dmitriy Granovskiy, Angelina Kovalenko, Marina Arkhipenko, Nikolai Nikitin, Olga Karpova   +8 more
doaj   +1 more source

Impact of novel coronavirus infection on urogenital system. Immunonutrition as a method of pathogenetic therapy in patients with COVID-19

Клинический разбор в общей медицине, 2021
On December 12, 2019, the novel coronavirus was identified in Wuhan, China, which caused the outbreak of severe acute respiratory syndrome (COVID-19) in human population, spreading rapidly all over the world; on March 11, 2020 the World Health ...
Ekaterina V. Kulchavenya
doaj   +1 more source

ZDHHC18‐Mediated Palmitoylation of ORF3a Promotes SARS‐CoV‐2 Pathogenesis by Antagonizing TRIM16‐Mediated Ubiquitination and Proteasomal Degradation

Advanced Science, EarlyView.
Palmitoylation by ZDHHC18 blocks ORF3a K27‐linked ubiquitination mediated by TRIM16, thereby preventing its proteasomal degradation and strengthening viral pathogenesis. Targeting palmitoylation through a pharmacological inhibitor (2‐BP), a competitive inhibitory peptide (OPIP), or adenovirus‐mediated knockdown of ZDHHC18 expression presents a ...
Sidi Yang, Kun Li, Lihong Liu, Linsen Zeng, Qifeng Deng, Jiacheng Huang, Xiaoran Dong, Xin Wang, Jianwei Liang, Hongchao Liu, Hong Peng, Yuxin Lin, Xiaolu Xie, Yuzhen Ye, Tiefeng Xu, Zhaohuan Wang, Chun‐Mei Li, Deyin Guo   +17 more
wiley   +1 more source

Incidence of Creutzfeldt-Jakob disease in Switzerland. [PDF]

, 2002
The incidence of Creutzfeldt-Jakob disease (CJD) in Switzerland increased two-fold in 2001, and figures from the first quarter of 2002 indicate that it continues to rise.
Glatzel, M, Ghani, A, Streffer, J R, Rogivue, Colette, Streffer, Johannes R, Aguzzi, Adriano, Amsler, L, Glatzel, Markus, Amsler, Lorenz, Rogivue, C, Aguzzi, A; https://orcid.org/, Ghani, Azra   +11 more
core   +1 more source

Changes in adolescents’ sleep during COVID-19 outbreak reveal the inadequacy of early morning school schedules [PDF]

Sleep Science
Objectives: The forced closure of schools during the COVID-19 outbreak imposed on adolescents a new reality of home-schooling. This new situation has affected adolescent sleep patterns due to the absence of the pressure to wake up earlier induced by ...
Jefferson Souza Santos, Fernando Mazzilli Louzada   +1 more
doaj   +1 more source

Humoral cross-reactivity towards SARS-CoV-2 in young children with acute respiratory infection with low-pathogenicity coronaviruses

Journal of Clinical Virology Plus, 2022
Background: SARS-CoV-2 infection in children frequently leads to only asymptomatic and mild infections. It has been suggested that frequent infections due to low-pathogenicity coronaviruses in children, impart immunity against SARS-CoV-2 in this age ...
Nitin Dhochak, Tanvi Agrawal, Heena Shaman, Naseem Ahmed Khan, Prawin Kumar, Sushil K. Kabra, Guruprasad R. Medigeshi, Rakesh Lodha   +7 more
doaj   +1 more source