Results 121 to 130 of about 402,323 (301)

S. aureus colonization and clinical symptoms remain stable upon topical XZ.700 treatment: Results of a double‐blind randomized clinical trial in patients with mild to moderate atopic dermatitis

British Journal of Clinical Pharmacology, EarlyView.
Aim Recovering dysbiosis may improve atopic dermatitis (AD) symptoms. XZ.700 is a recombinant chimeric endolysin that specifically targets Staphylococcus aureus and could be a new treatment option for patients with AD. The aim of this first‐in‐human study was to evaluate the safety, tolerability and efficacy of topical XZ.700 and explore the ...
Laura W. J. van der Meulen, Menthe E. Bergmans, Salma Assil, Naomi Klarenbeek, Marieke L. de Kam, Alexa J. Tibboel, Thorsten Brach, Bjorn L. Herpers, Johan Frieling, Vincent de Jong, Benthe Freyee, Martijn B. A. van Doorn, Robert Rissmann, Tessa Niemeyer–van der Kolk   +13 more
wiley   +1 more source

Guidance for preventive and responsive measures to coronavirus for youth agencies [PDF]

, 2020
The coronavirus, or COVID-19, has been declared by the World Health Organization to be a global pandemic. As the number of people infected in the United States grows exponentially, we must focus on prevention and containment in the criminal and ...
Vera Institute of Justice
core  

The epidemiology of variant Creutzfeldt-Jakob disease [PDF]

, 2002
Variant Creutzfeldt-Jakob disease (vCJD) was identified as a new disease in 1996. It was linked to infection with the bovine spongiform encephalopathy (BSE) agent although the epidemiological evidence for this was not strong, but later strain typing ...
d' Huillard Aignaux, JN, S. N. Cousens, P. G. Smith, Smith, PG, J. N. Huillard d’Aignaux, Ghani, AC, Azra C. Ghani, Ward, HJT, R. G. Will, Cousens, SN, Will, RG, Huillard d'Aignaux, JN, H. J. T. Ward   +12 more
core   +1 more source

Pharmacokinetics and safety of tezepelumab in children with mild, moderate or severe asthma and adolescents with mild‐to‐moderate asthma

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tezepelumab is a human monoclonal antibody that blocks the activity of thymic stromal lymphopoietin and is approved for adolescents and adults with severe asthma. This analysis assessed pharmacokinetics (PK), pharmacodynamics and safety of tezepelumab up to 85 days postdose in adolescents and children.
Anna Lundahl, Jonathan Grigg, Lubna Abuqayyas, Piotr Kuna, Gillian Hunter, Beata Pawlikowska, Jacob Leander, Michael Levin, Atul Gupta, James Paton, Katharine C. Pike, Jane R. Parnes, Gun Almqvist, Stephanie L. Roseti, on behalf of the study investigators   +14 more
wiley   +1 more source

Guidance for preventive and responsive measures to coronavirus by police and law enforcement [PDF]

, 2020
The coronavirus, or COVID-19, has already been declared by the World Health Organization as a global pandemic. As the number of people infected in the United States grows exponentially, we must focus on prevention and containment in the criminal and ...
Vera Institute of Justice
core  

Comparison of the risks of atherosclerotic events versus death from other causes associated with antiretroviral use. [PDF]

, 2006
BACKGROUND: Studies considering the risk of atherosclerotic disease (AtD) associated with the use of HAART have reported inconsistent results. METHODS: Data on antiretroviral therapy (ART) use, risk factors for cardiovascular disease (CVD), AtD and death
de Wolf, Frank, Kwong, Grace PS, Ghani, Azra C, Cameron, D William, da Silva, Barbara, Cowling, Benjamin J., Danner, Sven A., Cameron, D. William, De Wolf, F, Ghani, AC, Anderson, RM, Bartley, Lucy M, van Sighem, Ard I, Bartley, LM, Kwong, GPS, Cowling, Benjamin J, Van Sighem, AI, Danner, SA, Donnelly, CA, Donnelly, Christl A., Ghani, Azra C., Anderson, Roy M, Danner, Sven A, Rode, Richard A, Rode, Richard A., Donnelly, Christl A, Da Silva, B, Bartley, Lucy M., Cowling, BJ, Cameron, DW, Van Sighem, Ard I., Rode, RA, Kwong, Grace P.S., Anderson, Roy M.   +33 more
core   +1 more source

Characterization and immunogenicity of nanoparticle vaccines displaying embecovirus spike proteins

Biotechnology Progress, EarlyView.
Virus‐like particle vaccines displaying spike proteins from OC43, HKU1 A, and HKU1 B were evaluated in mice for their ability to elicit antibodies against the spike proteins from OC43, HKU1 A, HKU1 B, and HKU1 C. Abstract Endemic human coronaviruses OC43 and HKU1 cause widespread respiratory infections and can be associated with severe illness in ...
Peter J. Halfmann, Augustine Duffy, Alex Wee, Noah Anderson, Jackson Terrell, Yoshihiro Kawaoka, Ravi S. Kane   +6 more
wiley   +1 more source

Guidance for preventive and responsive measures to coronavirus for parole, probation, and clemency [PDF]

, 2020
The coronavirus, or COVID-19, has already been declared by the World Health Organization as a global pandemic. As the number of people infected in the United States grows exponentially, we must focus on prevention and containment in the criminal and ...
Vera Institute of Justice
core  

Knowledge of and attitudes toward COVID-19 among parents of child dental patients during the outbreak

Brazilian Oral Research
: The aim of this study was to evaluate the knowledge of and attitudes toward coronavirus disease 2019 (COVID-19) among the parents of child dental patients in Shenzhen during the outbreak. A structured questionnaire containing 10 questions was used, and
Jin Sun, Yan Xu, Qian Qu, Wei Luo
doaj   +1 more source

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, EarlyView.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source