Results 131 to 140 of about 402,323 (301)

Zoonotic coronavirus infections [PDF]

, 2019
Coronaviruses have long been known as important pathogens in the veterinary field that can cause severe diseases in livestock and companion animals. In humans, however, coronaviruses have essentially been neglected for a long time since they were known ...
Kratzel, Annika, Pfaender, Stephanie, Thiel, Volker   +2 more
core  

Substrate‐Selective Inhibition of the SARS‐CoV‐2 Papain‐Like Protease: Inhibition of Hydrolysis of Human Over Viral Substrates

Chemistry – A European Journal, EarlyView.
The SARS‐CoV‐2 papain‐like protease (PLpro) is a medicinal chemistry target. Here we report mass spectrometry assays employing oligopeptide substrates based on the sequences of the viral polyproteins 1a/1ab and on an ISG15‐modified human protein, which enabled the identification of substrate‐selective PLpro inhibitors.
Sakshi Sharma, Peter A. C. Wing, Wojtek Treyde, Shyam Basak, Simeon D. Draganov, Taylah Andrews‐Clark, Eidarus Salah, Petra Lukacik, Claire Strain‐Damerell, Adán Pinto‐Fernández, Martin A. Walsh, Fernanda Duarte, Christopher J. Schofield, Lennart Brewitz   +13 more
wiley   +1 more source

COVID-19 in children under 20 years of age of the province of Camagüey

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2020
Full text (en español)
Maribys Téllez-Lorente
doaj  

Iranian Smell Diagnostic Test in Covid-19 Disease; Report of Covid-19 Center of North of Iran

Caspian Journal of Internal Medicine, 2022
Background: SARS-CoV-2 is a pandemic coronavirus that causes the COVID-19 syndrome. In the pandemic of COVID-19 many patients were affected to new onset olfactory dysfunction. Since there is a dearth of research studies regarding the standard smell test,
Shayan Alijanpour, Payam Saadat, Mehran Shokri, Sepanta Saadat, Azam Khodami   +4 more
doaj  

MultNAT HPV16/18 Assay: A Simple, Rapid, and Low‐Cost Polymerase Chain Reaction Method for the Detection of HPV16 and HPV18 Suitable for Point‐of‐Care Testing

Cancer Nexus, EarlyView.
ABSTRACT Aim Persistent high‐risk HPV infection can lead to the development of precancerous lesions, potentially progressing to invasive cancer. HPV status serves not only as a prognostic marker for squamous cell carcinoma (HNSCC) like oropharyngeal squamous cell carcinomas (OPSCC) but also significantly influences clinical management and treatment ...
Min Wang, Yueping Li, Qingting Bu, Peng Xiong, Suhang Li, Xiaoyan Li, Sisi Chen, Yanqiong Zhou, Siyu Li, Xiaojuan Jia   +9 more
wiley   +1 more source

Quantifying HIV-1 transmission due to contaminated injections. [PDF]

, 2007
Assessments of the importance of different routes of HIV-1 (HIV) transmission are vital for prioritization of control efforts. Lack of consistent direct data and large uncertainty in the risk of HIV transmission from HIV-contaminated injections has made ...
Whitworth, J, Korenromp, Eline, Baggaley, Rebecca F, Korenromp, EL, Biraro, S, Cooper, BS, Kedhar, A, Boily, MC, Korenromp, Eline L, Ghani, Azra, White, Richard G, Hayes, Richard J, White, RG, Ghani, A, Biraro, Sam, Orroth, KK, Baggaley, RF, Kedhar, Anusha, Boily, Marie-Claude, Ben, S Cooper, Ben, SC, Orroth, Kate K, Whitworth, Jimmy, Hayes, RJ   +23 more
core   +1 more source

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

Electron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary, Harsh Sable, Sonu Sonu, Lakshita Phor, Reddicherla Umapathi, Pradeep Bhadola   +5 more
wiley   +1 more source

The transmission dynamics of BSE and vCJD. [PDF]

, 2002
The bovine spongiform encephalopathy (BSE) epidemic in cattle has had a huge economic impact on the agricultural industries across Europe. Furthermore, scientific evidence now strongly supporting a link between a new variant of Creutzfeldt-Jakob disease (
Ghani, Azra C, Donnelly, Christl A, Azra C. Ghani, Christl A. Donnelly, Anderson, Roy M, Neil M. Ferguson, Roy M. Anderson, Ferguson, Neil M   +7 more
core   +1 more source

Oral manifestations in patients with COVID-19 treated in an isolation center in Las Tunas

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2021
Background: oral manifestations associated with COVID-19 patients may appear prior to respiratory symptoms, during and after the course of the disease.Objective: to describe the oral manifestations in patients with COVID-19 treated at the “Los Cocos ...
Taimí Santos-Velázquez, Lisvan Aciet-Cruz   +1 more
doaj  

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source