Results 151 to 160 of about 402,323 (301)

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

Approbation of the Technology for Constructing Means of Express Indication of New Especially Dangerous

Вестник войск РХБ защиты
Catastrophic pandemic of the particularly dangerous coronavirus SARS-CoV-2 in 2020–2022 and the unexpected  spread of the monkeypox pathogen from Africa in 2022, demonstrate the need for an adequate response to biological  threats that have exotic ...
A. A. Petrov, A. V. Kazantsev, K. A. Panferov, A. A. Chislov, E. A. Kovalchuk, D. A. Kutaev, S. V. Borisevich   +6 more
doaj   +1 more source

Mixed lineage kinase 3 mediates SARS‐CoV‐2‐induced kidney injury via the Hsp70‐IL‐17A axis

Interdisciplinary Medicine, EarlyView.
Kidney samples from patients infected with severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) showed upregulated expression and activity of Mixed Lineage Kinase (MLK3). Based on the mechanistic studies, we identified MLK3 as a critical player in promoting SARS‐CoV‐2‐induced kidney injury.
Sandeep Kumar, Sunil Kumar Singh, Piush Srivastava, Sowdhamini Mahendiran, Rakesh Sathish Nair, Harsh Vyas, Saket Jha, Niraj Nag, Navin Viswakarma, Hitesh Kapoor, Swathi Suresh, Periannan Sethupathi, Sang‐Ging Ong, Jerrold S. Levine, Suman Setty, Mathayan Manikannan, Bellur S. Prabhakar, Basabi Rana, Ajay Rana   +18 more
wiley   +1 more source

Guidance for preventive and responsive measures to coronavirus for rural justice systems [PDF]

, 2020
The coronavirus, or COVID-19, has been declared by the World Health Organization to be a global pandemic. As the number of people infected in the United States grows exponentially, we must focus on prevention and containment in the criminal and ...
Vera Institute of Justice
core  

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source

Human Coronavirus Infections [PDF]

, 1995
The first report of a human coronavirus was in 1965 when Tyrrell and Bynoe (1965) isolated a virus from the nasal washings of a male child. The child had typical symptoms and signs of a common cold and the washing was found to be able to induce common colds in volunteers challenged intranasally.
openaire   +1 more source

Serum Apelin‐13 and Galectin‐3 in COVID‐19: Associations With Routine Biochemical Parameters and Diagnostic Performance in a Case–Control Study

Journal of Clinical Laboratory Analysis, EarlyView.
Serum Apelin‐13 and Galectin‐3 levels were measured by ELISA in COVID‐19–positive patients and controls and evaluated alongside routine biochemical parameters. COVID‐19 patients showed significant alterations in liver, renal, inflammatory, and metabolic markers.
İsmail Uğurlu
wiley   +1 more source

Prevalence and costs of US pediatric hospitalizations, 2022

Journal of Hospital Medicine, EarlyView.
Abstract Background Pediatric hospitalizations represent an evolving component of US healthcare utilization. The coronavirus disease 2019 (COVID‐19) pandemic hastened rising mental health visits and shrinking rural hospital capacity. Understanding contemporary patterns in pediatric hospitalizations is critical to inform health system planning and ...
Anna J. Lytchakov, Nathan M. Money, Jennifer A. Hoffmann, Todd A. Florin, Kenneth A. Michelson, Sriram Ramgopal   +5 more
wiley   +1 more source

Scheduling early primary care follow‐up after pneumonia: A retrospective target trial emulation in five hospitals

Journal of Hospital Medicine, EarlyView.
Abstract Background Current guidelines make no recommendations on discharge interventions or scheduling outpatient follow‐up after hospitlization for commnity‐acquired pneumonia (CAP). Objectives To assess the impact of scheduling early primary care follow‐up prior to discharge home among survivors of hypoxemic CAP hospitalizations.
Andrew J. Davis, Stephanie P. Taylor, Catherine L. Hough, Mari Armstrong‐Hough, Li Yan, Catherine K. Ettman, Katy Sadowski, Khyzer B. Aziz, Patrick G. Lyons, Katrina E. Hauschildt, Marc Kowalkowski, Eliana M. Perrin, Theodore J. Iwashyna   +12 more
wiley   +1 more source

Proviral role of caspase-6 in coronavirus infections. [PDF]

Cell Res, 2023
Wong LR, Perlman S.
europepmc   +1 more source