Results 281 to 290 of about 494,023 (345)

Prevalence of Eight Viruses in Captive Amur Tigers (Panthera tigris altaica) From Harbin, China 中国哈尔滨市圈养东北虎8种病毒的流行

open access: yesWildlife Letters, EarlyView.
The Amur tiger, an endangered flagship species mainly found in the Russia Far East and Northeastern China, holds immense biological importance, and has been listed under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES).
Wei Xie   +15 more
wiley   +1 more source

Crystallographic fragment screening against SARS‐CoV‐2 nonstructural protein 1 using the F2X‐Entry Screen and a newly developed fragment library

open access: yesActa Crystallographica Section D, EarlyView.
Two crystallographic fragment screening campaigns against SARS‐CoV‐2 nonstructural protein 1 resulted in the identification of 21 new hits.Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) continues to threaten global health. This underpins the need for novel therapeutics against this virus.
Frank Lennartz   +9 more
wiley   +1 more source

Real‐World Safety Profile of Spesolimab in Generalized Pustular Psoriasis: Insights From Japan as Part of a Multinational Expanded Access Program (EAP)

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Generalized pustular psoriasis (GPP) is a heterogeneous, systemic neutrophilic inflammatory disease, characterized by chronic symptoms and recurrent flares, which can be potentially life‐threatening. Spesolimab, an interleukin‐36 receptor antagonist, has been approved to treat GPP flares in many countries including Japan.
Akimichi Morita   +12 more
wiley   +1 more source

Therapeutic Efficacy of the Supersulfide Donor NAC‐S2 in Influenza Virus Pneumonia via Suppression of Excessive Inflammatory Responses

open access: yesMicrobiology and Immunology, EarlyView.
ABSTRACT Influenza pneumonia is characterized by excessive inflammatory responses that contribute to severe lung injury and mortality. Supersulfides, endogenously produced cysteine‐derived persulfides and polysulfides, exert potent antioxidant, anti‐ferroptotic, and anti‐inflammatory activities; however, their therapeutic potential after disease onset ...
Foysal Hossen   +9 more
wiley   +1 more source

Nordic legal overseers and institutional openness in crises: Challenges and adaptation during the COVID‐19 pandemic

open access: yesScandinavian Political Studies, EarlyView.
Abstract We analyze challenges and adaptation strategies of Nordic legal overseers, the Parliamentary Ombudsmen and Chancellors of Justice in Denmark, Finland, Norway and Sweden, amid the COVID‐19 crisis. We study how the accountability capacities of the legal overseers were affected when standard practices of inclusive decision‐making were severed ...
Tero Erkkilä   +2 more
wiley   +1 more source

EXPERIENCING MORE‐THAN‐PANDEMIC WATERSCAPES: An Intra‐urban Comparison of Water Practices and Geographies in Nairobi

open access: yesInternational Journal of Urban and Regional Research, EarlyView.
Abstract While many African cities, such as Nairobi, fared comparatively well during the pandemic years, urban residents still faced compounded uncertainties and an unequal distribution of burdens that were infrastructurally co‐mediated, for example, within and through place‐specific waterscapes and their socio‐technical infrastructures.
Moritz Kasper   +2 more
wiley   +1 more source

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