Results 31 to 40 of about 184,665 (228)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Empowerment of the Few and Disempowerment of the Many - Disempowerment in Thai ‘One Tambon One Product' Organizations (OTOPS) [PDF]
, 2016 Thai ‘One Tambon One Product’ organisations (OTOPs) have had considerable economic suc-cess since their initiation by the Thai government in 2001. However, in contrast to their ever-increasing economic relevance, OTOPs’ contributions to
Diefenbach, T. (Thomas)
core
Applying the ideas of Bernstein in the context of in-company management education [PDF]
, 2007 Ideas drawn from the sociology of education have had surprisingly little impact on debates on organizational learning. This article takes ideas drawn from the sociology of education and applies them to a subset of organizational learning, the rapidly ...
Mutch, A
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Credit Card Fraud: A New Perspective On Tackling An Intransigent Problem [PDF]
, 2011 This article offers a new perspective on battling credit card fraud. It departs from a focus on post factum liability, which characterizes most legal scholarship and federal legislation on credit card fraud and applies corrective mechanisms only after ...
Mana, Jafar +2 more
core +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Managing Wireless Networks in the Healthcare Sector: Emerging Experiences of Cultural Impacts [PDF]
, 2010 The existing body of knowledge has generally supported that organizational culture plays a significant role in shaping group identity, work pattern, communication schemes, and interpersonal relations; all of these cultural elements are important ...
Bennett, David, Chen, Wenshin
core +2 more sources
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
School Naming Rights and the First Amendment’s Perfect Storm [PDF]
, 2007 In the past five years, public schools across the country have begun to explore a new avenue of fundraising: selling naming rights to school facilities. The popularity and monetary value of these sales, however, only highlight the importance of the First
Karlsson, Maria, Lager, Johanna
core +2 more sources