Results 21 to 30 of about 184,665 (228)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Workplace Contextual Supports for LGBT Employees: A Review, Meta‐Analysis, and Agenda for future Research [PDF]

, 2018
The past decade has witnessed a rise in the visibility of the lesbian, gay, bisexual, and transgender (LGBT) community. This has resulted in some organizational researchers focusing their attention on workplace issues facing LGBT employees.
Allan, Allen, Anderson, Androsiglio, Armstrong, Badgett, Balzer, Barak, Baruch-Feldman, Becker, Beehr, Bennett, Blau, Bowen, Boyles, Brackmann, Brenner, Brewster, Brooks, Budescu, Butler, Button, Button, Cameron, Cammann, Caplan, Carr, Chrobot-Mason, Clair, Cobb, Cohen, Combs, Croteau, Croteau, Curtis, Dawis, Day, Day, Derogatis, Drake, Driscoll, Dwertmann, Eisenberger, Eisenberger, Ellis, Fasoli, Ferris, Frankenhaeueser, Friskopp, Ganster, Gardner, Gates, Gould-Williams, Grant, Griffith, Hasenbush, Hebl, Herek, Hope Pelled, House, Huebner, Huffman, Hunter, Hunter, Ironson, James, James, Ji, Johnston, Judge, Kahn, Kehoe, King, King, Konrad, Kossek, Kristof, Kulik, Law, Liddle, Macky, Martin, Martin, May, McDermott, McKay, Meyer, Meyer, Meyer, Mohr, Mowday, Munoz, Norton, Osipow, Ostroff, Parker, Parker, Passani, Posthuma, Quinn, Quinn, Quinn, Rabelo, Ragins, Ragins, Ragins, Ragins, Rankin, Reed, Roberson, Robinson, Rostosky, Ruggs, Saari, Sabat, Schaufeli, Schein, Schein, Sears, Smith, Spence, Spreitzer, Subramony, Tejeda, Thoits, Trau, Ueno, Velez, Viswesvaran, Waldo, Weiss   +130 more
core   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Corporate communications: audiences, funding and crisis management [PDF]

, 2000
Who are the key audiences of corporate communications? Is the communication department adequately funded? And how are crisis handled? This paper reports an empirical research conducted in 20 British organisations, with a focus on these three questions ...
Dolphin, R, Fan, Y
core  

Do UK universities communicate their brands effectively through their websites? [PDF]

, 2011
This paper attempts to explore the effectiveness of UK universities’ websites. The area of branding in higher education has received increasing academic investigation, but little work has researched how universities demonstrate their brand promises ...
Aaker D. A., Ana Castillo Díaz, Baker M., Barthes R., Carrillo V., Chris Chapleo, Clark R. B., Field A. P., Gibbs G., Gombrich E. H., Grundey D., Hair J. F., Johnson A., Kapferer J. N., Keller K. L., Kotler N., Lache S., Lynch P. J., María Victoria Carrillo Durán, Marín A., Miles M. B., Nielsen J., Pickton D., Pringle H., Ragin C., Ragin C., Schultz M., Smithson M. J., Stamp R., Stensaker B., Terano T., Tryon R. C., Varey R. J., Villafañe J.   +33 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Are They for Real? Activism and Ironic Identities [PDF]

, 2008
A new breed of political activist has begun to appear on the streets and in the news. They are no longer trying to out-shout their opponents, but are agreeing with them instead, enthusiastically taking their adversary’s position to exaggerated extremes ...
Day, Amber
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source