Results 161 to 170 of about 9,165,708 (258)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Corporate social responsibility in a general equilibrium stock market model: Solving the financial performance puzzle [PDF]

open access: yes
We analyze corporate social responsibility (CSR) in a general equilibrium stock market model with uncertainty in production. Production generates non-market costs and consumers take this into account when they construct their portfolio.
Dam, Lammertjan
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Does financial performance enhance corporate governance on firm performance?

open access: yes, 2015
碩士本研究主要是探討財務表現會增強公司治理對公司績效的影響,並一併探討公司治理是否也會增強財務表現對公司治理的影響。在本文中,公司治理變數採用董監事持股與董監事質押此二變數,財報變數為負債比率、資產周轉率及淨利率此三變數。並獲致以下重要發現:其一、董監事持股確實能夠增強資產周轉率與淨利率對公司績效的影響,而董監事質押則會削弱資產周轉率對公司績效的影響。其二、負債比率反而不會增強董監事質押對公司績效負面影響,亦為兩者並存其負面影響反而會削弱,因為加劇可能無法讓公司在資本市場上存活。其三 ...
江昇達; Chiang, Sheng-Ta
core  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Managerial ownership and corporate performance in Slovenian post-privatisation period [PDF]

open access: yes
The Slovenian post-privatisation period has been characterised by a decline in the ownership by non-managerial owners (employees) and state-controlled funds.
Marko Simoneti, Aleksandra Gregoric
core  

Circular causality analysis of corporate performance and accounting quality in M&As. [PDF]

open access: yesPLoS One
Herghiligiu IV   +5 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy