Results 101 to 110 of about 470,641 (272)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

From Offloading to Engagement: An Experimental Study on Structured Prompting and Critical Reasoning with Generative AI

Data
The rapid adoption of generative AI raises questions not only about its transformative potential but also about its cognitive and societal risks. This study contributes to the debate by presenting cross-country experimental data (n = 150; Germany ...
Michael Gerlich
doaj   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Exploring Motivators for Trust in the Dichotomy of Human—AI Trust Dynamics

Social Sciences
This study analyses the dimensions of trust in artificial intelligence (AI), focusing on why a significant portion of the UK population demonstrates a higher level of trust in AI compared to humans.
Michael Gerlich
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

COVID-19 impact and resilience mechanisms in Limpopo province’s farming communities

Discover Food
The differential impacts of COVID-19 on small, medium, and large-scale farmers in South Africa are still not fully understood, creating challenges for resilience to future pandemics.
Lazarus Chapungu, Godwell Nhamo, Munyaradzi Chitakira, Khangwelo Desmond Musetsho   +3 more
doaj   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Relationship between the Disclosure of Sustainability with the Corporate Governance: A Study in Companies Listed in Ibrx-100

Revista Sociedade, Contabilidade e Gestão, 2015
The aim of this study was to investigate the relationship between the disclosure of sustainability with some features of corporate governance in publicly traded Brazilian firms.
Emanoel Truta do Bomfim, Wellington dos Santos Teixeira, Paulo Aguiar do Monte   +2 more
doaj  

Toward a Sustainable Paradigm: Redefining Corporate Purpose in the EU Context

Systems
Recent societal transformations have intensified debates on corporate purpose, yet empirical evidence linking these debates to measurable sustainability outcomes remains fragmented.
Claudiu George Bocean, Anca Antoaneta Vărzaru   +1 more
doaj   +1 more source

Occupational Safety & Health Management and Corporate Sustainability: The Mediating Role of Affective Commitment. [PDF]

Saf Health Work, 2023
Tan ZC, Tan CE, Choong YO.
europepmc   +1 more source