Results 81 to 90 of about 19,226 (249)

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Relationship between the Disclosure of Sustainability with the Corporate Governance: A Study in Companies Listed in Ibrx-100

open access: yesRevista Sociedade, Contabilidade e Gestão, 2015
The aim of this study was to investigate the relationship between the disclosure of sustainability with some features of corporate governance in publicly traded Brazilian firms.
Emanoel Truta do Bomfim   +2 more
doaj  

Toward a Sustainable Paradigm: Redefining Corporate Purpose in the EU Context

open access: yesSystems
Recent societal transformations have intensified debates on corporate purpose, yet empirical evidence linking these debates to measurable sustainability outcomes remains fragmented.
Claudiu George Bocean   +1 more
doaj   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown   +6 more
wiley   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

AI Tools in Society: Impacts on Cognitive Offloading and the Future of Critical Thinking

open access: yesSocieties
The proliferation of artificial intelligence (AI) tools has transformed numerous aspects of daily life, yet its impact on critical thinking remains underexplored. This study investigates the relationship between AI tool usage and critical thinking skills,
Michael Gerlich
doaj   +1 more source

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