Results 71 to 80 of about 2,922,340 (285)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Narrative reporting by UK charities [PDF]
, 2013 This study is the first in-depth study of the form and content of the narrative element of charities’ reporting documents. It offers insights into why charities choose to disclose (or not disclose) in their public reporting documents.Publisher ...
Connolly, Ciaran, Dhanani, Alpa
core +2 more sources
Climate-related financial effects: Disclosure challenges after Corporate Sustainability Reporting Directive implementation [PDF]
Zeszyty Teoretyczne RachunkowościPurpose: The article compares the disclosure requirements under the Corporate Sustainability Reporting Directive (CSRD) and European Sustainability Reporting Standards (ESRS) E1 “Climate Change” with the actual scope of disclosures on climate-related ...
Paweł Szalacha
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Corporate social responsibility reporting in mainland China [PDF]
, 2012 Although CSR has been the subject of substantial academic research for more than half a century, the CSR literature is dominated by empirical studies in the industrialized countries. There is limited knowledge on how CSR is perceived and implemented by
Du, Yaning
core +2 more sources
Future Business JournalEnvironmental sustainability is a global concern for governments, companies, investors and consumers. The efforts made by companies to improve sustainability are reflected in their reports.
Elena Rivo-López +3 more
doaj +1 more source
Romanian Economic JournalThe regulatory framework of reporting in Europe is becoming increasingly complex, where the main goal of reporting is to strengthen transparency in the publication of information related to environmental, social and governance (ESG) issues, the so-called
Nikolina Dečman
doaj +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Assessment of Polish companies’ preparedness for ESG reporting in the context of its determinants as evaluated by report preparers [PDF]
Zeszyty Teoretyczne RachunkowościPurpose: The purpose of this article is to assess the degree and scope of preparedness of Polish companies for Environmental, Social, and Governance (ESG) reporting from the perspective of respondents engaged in environmental reporting, taking into ...
Aleksandra Sulik-Górecka +2 more
doaj +1 more source
Managing Sustainability Data Proactively: Corporate Sustainability Reporting (Directive) as a Driver
Information Systems JournalABSTRACT Sustainability has become a key priority for firms, and the increasing number of mandatory regulations only heightens its importance. The Corporate Sustainability Reporting Directive (CSRD) introduces stringent non‐financial disclosure requirements, significantly expanding the scope and breadth of reporting, particularly for ...
Elizabeth A. Teracino +2 more
openaire +1 more source