Results 41 to 50 of about 3,209,211 (360)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
E-SpaniaLa constitution des cargadores a Indias, ces négociants spécialisés dans le commerce avec les Indes, en corporation, à partir de 1543, après la création du Consulado de mercaderes de Séville, marque un tournant dans la structuration sociale et économique
Victoria Villalba
doaj +1 more source
Capital social e a privatização do conhecimento Social capital and the privatization of knowledge
Sociologias, 2008 O trabalho examina o movimento intelectual que envolveu a reflexão científica nas ciências sociais a partir dos anos 1960 e suas vinculações com as transformações que, na mesma época, agitam as relações econômicas e políticas no plano mundial, com seu ...
Renato P. Saul
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Matrix of Actions Being Taken on FLA Recommendations [PDF]
, 2009 This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
Russell Corporation
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Brawijaya Law Journal, 2019 Indonesian laws have recognized the legal person as a subject of criminal law. It can be seen in all regulations enacted recently acknowledging that “any person” is a natural person (natuurlijk persoon) and legal person (rechtspersoon) who are liable for
Alfons Zakaria
doaj +1 more source
Remediation Action Plans (Jerzees de Choloma and Jerzees de Honduras) [PDF]
, 2007 This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
Russell Corporation
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Virtual general meetings [PDF]
Zbornik Radova: Pravni Fakultet u Novom SaduTraditionally, general meetings have been held as physical meetings. Over the last two decades, legislators have often allowed hybrid meetings, giving shareholders the right to participate both electronically and in person.
Radović Vuk G.
doaj +1 more source