Results 61 to 70 of about 3,209,211 (360)
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Japan' New Competitive Advantage: Enterprises' Innovative Initiatives and Government's Reforms [PDF]
, 2011 This article is a continuation of the report "Japan's new competitive advantage. Arguments and proposals for structural reorientation" published in the "Comparative Economic Research for Central & Eastern Europe", vol. 13, no 1/2/2010, which mainly dealt
Młodawska, Jolanta
core +2 more sources
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
The Importance of Corporation Law to Civil Society
Nonprofit Policy Forum, 2011 The thesis of this paper is that transactions costs related to formation of nonprofit corporations are restraining the size of the nonprofit sector in Europe. An unfettered ability to incorporate is an important determinant of nonprofit formation.
Bowman Woods
doaj +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Direct Environmental Standing for Chartered Conservation Corporations [PDF]
, 2001 This article suggests that, as an antidote to the ever-tightening restrictions on individual environmental standing, a state may charter a not-for-profit corporation organized to protect a particular environmental resource, giving the corporation a non ...
Coplan, Karl S.
core +2 more sources
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Responsibility and the modern corporation [PDF]
, 2018 Corporate governance crises as well as human rights issues in global value chains have pushed notions of Corporate Social Responsibility (CSR), Corporate Citizenship (CC), Triple P (People, Planet, Profit) and sustainable development onto the agenda of ...
Veldman, J.
core +1 more source
Building corporate reputation through corporate governance [PDF]
Management, 2008 The authors of the article deal with mutual relations of corporate governance and corporate reputation. The aim of this paper is to show that corporate governance design is in the function of better corporate reputation and to test the perceived relation between corporate governance and corporate reputation.
Cedomir Ljubojevic, Gordana Ljubojevic
openaire +2 more sources