Results 71 to 80 of about 37,407 (269)

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Global Retailing: An American Business? [PDF]

Ovidius University Annals: Economic Sciences Series, 2020
Since the end of the Second World War, retail has undergone a profound and long-term transformation all over the world. The second half of the twentieth century witnessed a structural shift from small and independent single-establishment retailers ...
Sorin-George Toma, Grădinaru Cătălin
doaj  

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Ontological approach to the normative dimension of organizations: an application of Documents Acts Ontology

Ciência da Informação, 2019
Modeling and knowledge representation are indispensable activities for developing information systems in the scope of modern corporations. In order to accomplish these activities, one should analyze a corporation both in terms of its physical structure ...
Maurício Barcellos Almeida, Mathias Brochhausen, Fabiana Bigão Silva, Renata Barcelos Moreira dos Santos   +3 more
doaj  

State's responsibility for business-related human rights violations in the light of the Strasbourg Court's case-law [PDF]

Pravni Zapisi, 2019
On the one hand, business entities have a huge potential to contribute to economic and social progress and consequently to the advancement of human rights. On the other, violations of human rights connected with business are very common.
Topić Boris
doaj  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Ontological approach to the normative dimension of organizations: an application of Documents Acts Ontology

Ciência da Informação, 2017
Modeling and knowledge representation are indispensable activities for developing information systems in the scope of modern corporations. In order to accomplish these activities, one should analyze a corporation both in terms of its physical structure ...
Maurício Barcellos Almeida, Mathias Brochhausen, Fabiana Bigão Silva, Renata Barcelos Moreira dos Santos   +3 more
doaj  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

MODELING OF CORPORATE STRUCTURES OF INDUSTRIAL ENTERPRISES

Вестник Дагестанского государственного технического университета: Технические науки, 2016
This article was first based on the use of complex mathematical models of dynamic programming analyzed the problem of optimizing the distribution of internal investment.As a result of research by the author for the first time demonstrated the model to ...
D. S. Таgaverdieva
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source