Results 101 to 110 of about 1,865 (266)
Le corps est la voie primordiale dans le processus d’énonciation, mais reste encore (trop) souvent corps étranger dans le processus d’enseignement/apprentissage des langues étrangères.
Alex Cormanski
doaj
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
ТЕОРЕТИЧЕСКИЕ ПОДХОДЫ К ПРЕДСТАВЛЕНИЮ О ТЕЛЕСНОСТИ У СОВРЕМЕННОЙ МОЛОДЕЖИ
Статья посвящена феномену телесности как одной из ключевой тем в современной мире и психологии. В данной статье рассматривается понятие телесность с позиции разных авторов и подходов.
Юрченко Е.В.
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
“He Has Music in Him”: Musical Moments, Dance and Corporeality in Joker (2019)
Danijela Kulezic-Wilson has discussed at length how the use of music in cinema adds to its corporeality and both fleshes out and gives life to otherwise spectral images.
Jessica Shine
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Lõhnapoeetika Carolina Pihelga romaanis „Vaadates ööd”
This article explores the representation of the sense of smell in Carolina Pihelgas’s novel “Looking at the Night” (Vaadates ööd, 2022). Among the senses, smell is particularly difficult to capture in language, often requiring the use of metaphors ...
Piret Põldver
doaj +1 more source

