Results 31 to 40 of about 57,417 (243)
Corps-matière et jouissance: le rêve d’un nouveau corps
Revista Subjetividades, 2016 Le succès et le partage planétaire d’une fantasmatique corporelle moderne: le scénario de la réinvention du corps et de sa “nature”, de la création d’un nouveau corps qui serait affranchi de la condition humaine, et les tentatives de tous ordres pour ...
Catherine Desprats Péquignot
doaj +2 more sources
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
La transparence du corps en médecine, obscur modèle de notre modernité
Appareil, 2011 La médecine contemporaine s’est constituée autour d’un regard tendant à rendre visible l’invisible selon la célèbre formule foucaldienne. De l’imagerie médicale aux récits médicaux de soi, l’ensemble de la médecine contemporaine semble régie par le ...
Alexandre Klein
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Corps contemporains : Évolutions numériques et changements esthétiques
Interfaces Numériques, 2018 L’article veut interroger les façons dont le numérique contribue à construire de nouvelles perceptions visuelles du corps. Il s’agit de repousser les limites du corps et de faire-faire de nouvelles expériences esthétiques et esthésiques du corps à un ...
Nanta Novello Paglianti
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Celle qui est de plus en plus danseuse depuis Degas. Danseuses et autres échos parisiens chez Almada Negreiros [PDF]
Synergies Portugal, 2017 Dans la revue Portugal futurista, Almada Negreiros avait écrit son poème « Mima Fataxa », hommage aux danseuses parisiennes, expression de l’utopie du corps en scène chère dans sa vie de peintre, dramaturge, scénographe et danseur.
Catarina Firmo
doaj
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source