Results 41 to 50 of about 57,010 (244)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

L’appareil numérique et la perspective ou le retour des espaces projectifs en art

open access: yesAppareil, 2008
Partant de l’idée que la technique n’est affaire ni d’infinité ni de vérité, cet essai interroge les conséquences de la technique et de la technoscience sur l’expérience du corps, de l’espace et du temps.
Michel Porchet
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

The power of markets: lessons from Uganda

open access: yesForced Migration Review, 2018
Market-based approaches in northern Uganda demonstrate the benefits of supporting local markets instead of distributing in-kind aid.
Alison Hemberger   +2 more
doaj  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

La symbolique du corps et pratique du tatouage en milieu Kinois [PDF]

open access: yesMouvements et Enjeux Sociaux, 2023
Le corps est une construction sociale et culturelle ; il est et devient davantage un objet de plusieurs représentations et d’imaginaires. C’est pour ces raisons que les individus arrivent à le manipuler et le transformer selon les besoins collectifs ou ...
Bienvenu MUKOSO NZO
doaj  

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

LANGAGE DU CORPS, CORPS DU LANGAGE. SUR UNE APPLICATION WÜSTERIENNE [PDF]

open access: yesStudii si Cercetari Filologice: Seria Limbi Romanice, 2008
Les recherches sur le lexique, en particulier dans le cadre des pratiques terminologiques, sont soumises à des renouvellements sous l’influence conjointe des domaines théoriques, des développements technologiques et des demandes sociales.
Narcis ZĂRNESCU
doaj  

Le souffle de l’histoire chez Georgette LeBlanc

open access: yesVoix Plurielles, 2016
Cet article porte sur le dialogue entre temps vécu et temps de l’histoire dans les quatre « romans poétiques » de l’auteure acadienne Georgette LeBlanc, étude qui s’appuie sur la parution récente du Grand feu (2016).
Julie St-Laurent
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

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