Results 71 to 80 of about 1,291,560 (300)

Challenges of releasing audio material for spoken data : The case of the London–Lund Corpus 2

open access: yes, 2021
This article aims to describe key challenges of preparing and releasing audio material for spoken data and to propose solutions to these challenges.
Johansson, Victoria   +12 more
core   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs   +7 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Corpus Linguistics

open access: yes, 2017
The chapter analyzes the contribution of CL to the study of dialogue and language as dialogue, with examples from English linguistics and academic discourse studies. CL has extended the possibilities of dialogue analysis and added to its theoretical-methodological perspectives. The chapter provides some background on CL, with special emphasis on spoken
Brysbaert, Marc   +2 more
openaire   +5 more sources

Pharmaceuticals in the blubber of live free-swimming common bottlenose dolphins (Tursiops truncatus)

open access: yesiScience
Summary: Pharmaceuticals prevent and treat diseases, yet inappropriate intake can result in harmful effects including mortality. Contaminants have become recurrent public and wildlife health concerns.
Anya Isabelle Ocampos   +6 more
doaj   +1 more source

Posterior Disconnection Syndrome in Early‐Stage Adult‐Onset Cerebral Adrenoleukodystrophy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adult‐onset cerebral adrenoleukodystrophy is potentially treatable but often difficult to recognize before advanced cerebral involvement. Herein, we describe three men with early‐stage disease who initially presented with subtle visual complaints rather than subcortical dementia. Targeted neuropsychological testing revealed higher‐order visual
Kazuto Katsuse   +13 more
wiley   +1 more source

Corpus-Based Transcription as an Approach to the Compositional Control of Timbre [PDF]

open access: yes, 2009
Timbre space is a cognitive model useful to address the problem of structuring timbre in electronic music. The recent concept of corpus-based concatenative sound synthesis is proposed as an approach to timbral control in both real- and deferred-time ...
Einbond, A., Bresson, J., Schwarz, D.
core   +2 more sources

Modeling Progressive Brain Volume Losses in Chronic Moderate Severe Traumatic Brain Injury: Extensive, but Attenuating

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progressive brain atrophy has now been widely observed in the chronic stages of moderate–severe traumatic brain injury (msTBI), but there is only coarse information regarding its prevalence and magnitude, and whether rate of atrophy accelerates or attenuates across time. We examined these questions in a Canadian inception cohort from
Robin E. A. Green   +6 more
wiley   +1 more source

Disparate Responses of Carbonate System in Two Adjacent Subtropical Estuaries to the Influence of Hurricane Harvey – A Case Study

open access: yesFrontiers in Marine Science, 2020
Two adjacent estuaries in the northwestern Gulf of Mexico (GOM) (Mission–Aransas or MAE and Guadalupe–San Antonio or GE), despite their close proximity and similar extents of freshening caused by Hurricane Harvey, exhibited different behaviors in their ...
Xinping Hu   +5 more
doaj   +1 more source

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