Results 91 to 100 of about 69,903 (252)

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

Advanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang, Ke‐Yu Zhang, Lang‐Jian Zhu, Wei‐Jue Li, Yang Wu, Xiang Gao, Xiao‐Ru Ma, Xiu‐Hua Yin, Jian‐Bin Wu, Xiao‐Kang Ye, Zhao‐Jun Dong, Di‐Xian Wang, Zhe Zhou, Shao‐Dong Wang, Lei Han, Zhi‐Nong Jiang, Jing‐Wei Zhao   +16 more
wiley   +1 more source

Intrinsic organization of the corpus callosum

Frontiers in Physiology
The corpus callosum—the largest commissural fiber system connecting the two cerebral hemispheres—is considered essential for bilateral sensory integration and higher cognitive functions. Most studies exploring the corpus callosum have examined either the
Paolo Barbaresi, Mara Fabri, Teresa Lorenzi, Andrea Sagrati, Manrico Morroni   +4 more
doaj   +1 more source

One-hundred years (and counting) of blast-associated traumatic brain injury [PDF]

, 2018
Blast-associated traumatic brain injury (TBI) has become one of the signature issues of modern warfare and is increasingly a concern in the civilian population due to a rise in terrorist attacks.
Fullerton, Josephine L., Kinch, Kevin, Stewart, William   +2 more
core   +1 more source

Corpus callosum–fastigium and tectal lengths in late‐onset small fetuses [PDF]

, 2023
D.L. Lip‐Sosa, M. Pérez‐Cruz, P. Ahumada‐Droguett, Teresa Ribas‐Prats, Marta Puertollano, Mario Antonio García-Gómez, Edurne Mazarico, E. Eixarch, Carles Escera, María Dolores Gómez‐Roig   +9 more
openalex   +1 more source

Assessing the Relative Importance of Imaging and Serum Biomarkers in Capturing Disability, Cognitive Impairment, and Clinical Progression in Multiple Sclerosis

Advanced Science, EarlyView.
Using machine‐learning analyses in two independent multiple sclerosis cohorts, spinal cord atrophy and cortical degeneration emerged as key predictors of disability and progression independent of relapses. Deep gray matter damage further improved prediction, while serum biomarkers of brain damage provided complementary information, highlighting the ...
Alessandro Cagol, Pascal Benkert, Sabine Schaedelin, Mario Ocampo‐Pineda, Noemi Montobbio, Po‐Jui Lu, Batuhan Ayci, Antonia Wenger, Alfi Aran Shukur, Kornelius Kaim, Lester Melie‐Garcia, Matthias Weigel, Alessio Signori, Pasquale Calabrese, Ludwig Kappos, Maria Pia Sormani, Jens Kuhle, Cristina Granziera   +17 more
wiley   +1 more source

Dysgenesis of corpus callosum with atretic occipital cephalocele

, 2021
Ammar Haouimi
openalex   +1 more source

The Microbiota Shapes Central Nervous System Myelination in Early Life

Advanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch, Emily G. Knox, Daniel Soong, Thomaz F. S. Bastiaanssen, Kalevi Trontti, Gabriel S. S. Tofani, Sophia Ivaschuk, Michael K. Collins, Donia Arafa, Jatin Nagpal, Iiris Hovatta, David A. Lyons, Gerard Clarke, John F. Cryan   +13 more
wiley   +1 more source

Lipoma of Corpus Callosum

Pediatric Neurology Briefs, 1988
A lipoma of the corpus callosum diagnosed by CT at 7 mos and mistaken for hemorrhage in a premature infant is reported from the Medical College of Pennsylvania, Philadelphia, PA.
J Gordon Millichap
doaj   +1 more source

Pediatric Bithalamic Anaplastic Astrocytoma Followed by Distant Progression to Glioblastoma in the Region of Corpus Callosum [PDF]

, 2021
Ivan Vukasinovic
openalex   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source