Results 61 to 70 of about 133,752 (286)

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Correlation Between Learning and Memory Impairment and Changes in Cerebral White Matter Nerve Fibers and Pericytes in Rats with Chronic Cerebral Ischemia

康复学报, 2022
ObjectiveTo analyze the correlation between the changes of learning and memory and the progressive degeneration of white matter nerve fibers and pericytes in the corpus callosum and hippocampus of rats with chronic cerebral ischemia, then to explore the ...
HUANG Jia, WANG Mengxue, NI Jinglei, LIANG Shengxiang, LIN Bingbing   +4 more
doaj  

Clinical features and prognosis analysis of acute corpus callosum infarction [PDF]

Jichu yixue yu linchuang
Objective To explore the clinical characteristics and prognostic analysis of acute corpus callosum infarction. Methods A total of 1 466 patients with acute cerebral infarction admitted to the Neurology Department of Jiangbin Hospital in Guangxi from ...
PENG Dingyue, WANG Weijing, ZHANG Wei, YANG Yi, BAO Zhuohua, LYU Yuan, LI Shujuan
doaj   +1 more source

Statistical Shape Analysis using Kernel PCA [PDF]

, 2006
©2006 SPIE--The International Society for Optical Engineering. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or ...
AD Roy, F Lee, G Jasso, GJ Borjas, GS Maddala, Herbert Brücker, J Schwarze, JJ Heckman, JJ Heckman, JR Harris, L Sjaastad, MC Burda, MC Burda, Parvati Trübswetter, R Willis, RA Nakosteen, S Goldfeld, WH Greene   +17 more
core   +3 more sources

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Recurrent deletions of ULK4 in schizophrenia : a gene crucial for neuritogenesis and neuronal motility [PDF]

, 2013
Peer reviewedPublisher ...
Blackwood, Douglas H, Gao, Guo-Dong, Guan, Zhen-Long, He, Guang, He, Lin, Hunter, Irene, Lang, Bing, Li, Wei-Dong, Liu, Min, Martin-Granados, Christina, McCaig, Colin D, Pu, Jin, Reilly, Thomas J, Shen, Sanbing, Shi, Yong-Yong, St Clair, David, Stefansson, Hreinn   +16 more
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Corpus callosum infarction with cognitive dysfunction: two case reports and literature review

Neuropsychiatric Disease and Treatment, 2018
Jianyu Zhang, Yi Tang, Yongan Sun, Yingda Xu, Lingen Pang, Jiaojiao Li, Taotao Wu, Mingli He Department of Neurology, Affiliated Lianyungang Hospital of Xuzhou Medical University, Lianyungang, Jiangsu, People’s Republic of China Introduction: The
Zhang J, Tang Y, Sun Y, Xu Y, Pang L, Li J, Wu T, He M   +7 more
doaj  

Mutations in SPG11, encoding spatacsin, are a major cause of spastic paraplegia with thin corpus callosum. [PDF]

, 2007
Autosomal recessive hereditary spastic paraplegia (ARHSP) with thin corpus callosum (TCC) is a common and clinically distinct form of familial spastic paraplegia that is linked to the SPG11 locus on chromosome 15 in most affected families. We analyzed
AZZEDINE H, BERTINI E, BOUSLAM N, BRICE A., CHARLES P, CHOMILIER J, CONFAVREUX C, COUTINHO P, CRUZ VT, DENORA PS, DURR A, ELLEUCH N, FILLA, ALESSANDRO, FONTAINE B, GRID D, LEGUERN E, LOSSOS A, LOUREIRO, JL, MARTIN E, OUVRARD HERNANDEZ AM, RUBERG M, SANTORELLI FM, STEVANIN G, TAZIR M, TESSA A   +24 more
core  

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source