Aberrant DNMTs Promote TXNIP Upregulation and Ovarian Fibrosis in PCOS
In a rat model of DHEA/DHT‐induced PCOS and in granulosa cells (GCs), upregulated DNMT1, DNMT3A, and DNMT3B inhibit TXNIP degradation, leading to TXNIP accumulation, which drives ovarian fibrosis and tissue injury. ABSTRACT Hyperandrogenism and elevated thioredoxin‐interacting protein (TXNIP) are potential causes of infertility in women with polycystic
Yajing Weng +12 more
wiley +1 more source
Studies relating to protein expression in the uterus of the cow [PDF]
End of project reportEmbryo loss is a major cause of reproductive wastage in the cow. The majority of embryo loss occurs in the first 16 days after fertilisation when the embryo is critically dependent on the maternal uterine environment for survival ...
Costello, L.M. +4 more
core
This study reveals a pivotal epigenetic regulatory role for the histone acetyltransferase p300, demonstrating that its acetylation of histone 3 at lysine 18 and 27 (H3K18ac and H3K27ac), alongside the formation of the p300/BRD4/SP1 complex, drives AR activation and ovarian fibrosis in PCOS.
Zhengquan Zhu +11 more
wiley +1 more source
ABSTRACT This study is the first to elucidate the oocyte growth pattern of Etroplus suratensis through detailed gonad histology. Ovary samples from different maturity stages were collected from October 2023 to September 2024 from cage culture systems installed in Vembanad Lake, Kumbalangi, Kerala, India.
Mohammad Saddam Hussain +8 more
wiley +1 more source
Post coital hemoperitoneum: The pain of love
Acute abdominal pain in women of reproductive age is common and frequent cause for visit to emergency department which warrants emergent evaluation.
Subramanian Senthilkumaran +4 more
doaj +1 more source
Reproductive Failure in UK Harbour Porpoises Phocoena phocoena : Legacy of Pollutant Exposure? [PDF]
This research was supported by a Marie Curie International Outgoing Fellowship within the Seventh European Community Framework Programme (Project Cetacean-stressors, PIOF-GA-2010-276145 to PDJ and SM).
Barber, Jonathan L. +11 more
core +6 more sources
Gendering the Menstrual Cycle in Behavioral Neuroendocrinology
ABSTRACT The menstrual cycle is increasingly described as a “vital sign of the female body,” with the literature suggesting cycle‐related brain and behavioral changes. With growing interest in the effects that the menstrual cycle has on the brain, body and mind, characterizing what constitutes healthy cycle‐related change has become a central goal of ...
Annie Duchesne +2 more
wiley +1 more source
Pre-implantation maternal uterine effects on embryo growth and development : an investigation using models of maternal constraint in sheep : a thesis presented in fulfilment of the requirements for the degree of Doctor of Philosophy in Animal Science, Massey University, Turitea, Palmerston North, New Zealand [PDF]
Listed in 2017 Dean's List of Exceptional ThesesPrenatal development and growth are critical to survival of the fetus and neonate. Recent evidence suggests that a critical period for determining growth is the pre-implantation period of pregnancy during
Fermin, Lisanne Monique
core
Basal Body Temperature Assessment: Is It Useful to Couples Seeking Pregnancy? [PDF]
Advanced practice nurses in primary care settings are often asked to give appropriate advice to couples seeking pregnancy. This article examines the issue of basal body temperature (BBT), a time-honored way to establish the presence of ovulatory cycles ...
Barron, Mary Lee, Fehring, Richard
core +1 more source
Molecular manipulation of keratin 8/18 intermediate filaments: modulators of FAS-mediated death signaling in human ovarian granulosa tumor cells [PDF]
Background: Granulosa cell tumors (GCT) are a rare ovarian neoplasm but prognosis is poor following recurrence. Keratin intermediate filaments expressed in these tumors are a diagnostic marker, yet paradoxically, may also constitute a target for ...
Davis, John S. +4 more
core +3 more sources

